7333-07-5Relevant academic research and scientific papers
Cooperative N-Heterocyclic Carbene/Nickel-Catalyzed Hydroacylation of 1,3-Dienes with Aldehydes in Water
Gao, Zhong-Hua,Han, You-Feng,Liu, Hao,Wang, Congyang,Ye, Song,Zhang, Chun-Lin
, p. 1657 - 1663 (2022/01/28)
The cooperative N-heterocyclic carbene/nickel-catalyzed redox-neutral hydroacylation of 1,3-dienes with aldehydes in water was reported. A wide range of aliphatic and aromatic aldehydes were directly coupled with 1,3-dienes, providing synthetically useful β,γ-unsaturated ketones or the corresponding ketones after hydrogenation in moderate to high yields and high atom economy. This protocol first demonstrated the compatibility of NHC catalysis with nickel catalysis. Water was used as the sole solvent, which is rarely reported in a cooperative metal/organic catalytic system.
A Direct Access to α-Diones from Oxalyl Chloride
Babudri, Francesco,Fiandanese, Vito,Marchese, Giuseppe,Punzi, Angela
, p. 7305 - 7308 (2007/10/02)
Cross-coupling reactions of oxalyl chloride with organocopper reagents, derived from Grignard reagents, cuprous bromide, and lithium bromide, provide a simple and straightforward method for the synthesis of symmetrical α-diones in very good yields.
Benzoin Condensation Reactions of 5-Membered Heterocyclic Compounds
Lee, Chang Kiu,Kim, Mi Soon,Gong, Jin Soon,Lee, In-Sook Han
, p. 149 - 153 (2007/10/02)
Benzoin condensation reactions of 2-thiophenecarboxaldehydes and furfurals have been reexamined with catalysts such as potassium cyanide, cyanide-resin, and a thiazolium salt. 2-Thiophenecarboxaldehydes gave both thenoins and thenils while furfurals gave only furoins.Possible routes which might lead to formation of thenils were investigated.
