734-79-2

Upstream product

• 19980-43-9 1-(trimethylsilyloxy)cyclopentene 
• 100-52-7 benzaldehyde 
• 62-53-3 aniline 
• 1750-36-3 (E)-N-benzylidenebenzenamine 
• 68081-15-2 1-tert-butyldimethylsilyloxycyclopentene 
• 120-92-3 cyclopentanone 
• 538-51-2 benzylidene phenylamine 
• 109-63-7 trifluoroborane diethyl ether 

Relevant academic research and scientific papers

An uncommon use of irradiated flavins: Br?nsted acid catalysis

We present that thioacetalization of aldehydes can be induced by blue light irradiation in the presence of a catalytic amount of riboflavin tetraacetate (RFTA) under aerobic conditions. Several control experiments have suggested that the reaction is more

Diastereoselective Mannich reaction with prolinated MWCNTs as a heterogeneous organo-nanocatalyst

Abstract: We intended to convert proline as a homogeneous catalyst to a heterogeneous catalyst by prolination of MWCNTs to improve proline efficiency as a catalyst by the ease of separating, catalytic economy, reusability, etc. To reach these goals, we sketched Pro-MWCNT catalyst and characterized it by different analyses such as FT-IR, SEM, EDX, CHNS. The efficiency of this heterogeneous catalyst was investigated and compared with proline homogeneous catalyst in Mannich reaction. The results hold out improvements in stereoselectivity, ease of separating and reusability. Graphic Abstract: This work represents an efficient and simple method to prepare Prolinated- MWCNTs as a heterogeneous organo-nanocatalyst. Prolinated-MWCNT was characterized by different analyses. The efficiency and catalytic activity of Pro-MWCNTs have investigated in mannich reaction, which has shown higher diastereoselectivity, moderate enantioselectivity, good reusability and high yields versus parent proline catalyst.[Figure not available: see fulltext.]

Surfactant-like Br?nsted acidic ionic liquid as an efficient catalyst for selective Mannich reaction and biodiesel production in water

Abstract: The current study deals with the applications of a surfactant-like Br?nsted acidic ionic liquid (IL) 1-dodecyl-3-methylimidazolium hydrogen sulfate ([DMIm]HSO4) for Mannich reaction at room temperature. The reaction was efficiently preceded in water as solvent without using any harmful and expensive organic additives. Our findings showed that the reaction is selective for cyclohexanone and no Mannich product was observed when cyclopentanone was used as starting material. Density functional theory (DFT) calculations were performed to provide an evidence about the nature of reactivity of the cyclohexanone/cyclopentanone. The activity of the catalyst was also tested for biodiesel production of fatty acids with methanol and ethanol at mild thermal condition without applying additional water removal steps such as using additives or performing special methodologies like azeotropic distillation. In both reactions, the IL can be recycled and reused several times with relatively constant efficiency. Graphical Abstract: [Figure not available: see fulltext.]

An efficient and mild bismuth triflate-catalysed three-component Mannich-type reaction

In the presence of a catalytic amount of Bi(OTf)3·4H 2O, aldehydes together with amines react with silyl enolates to afford the corresponding Mannich-type adducts smoothly. A wide variety of silyl enolates derived from ketones, as well as esters and thioesters, react rapidly to afford the β-amino ketones or the β-amino esters in high yields (up to 94%). The Royal Society of Chemistry.

Mannich-type reactions of aromatic aldehydes, anilines, and methyl ketones in fluorous biphase systems created by rare earth (III) perfluorooctane sulfonates catalysts in fluorous media

Rare earth (III) perfluorooctane sulfonates (RE(OPf)3) catalyze the three-component Mannich-type reactions of different ketones with various aromatic aldehydes and aromatic amines in fluorous media to give various β-arylamino ketones in good yields. By simple separation of the fluorous phase containing only catalyst, reaction can be repeated several times.

Molecular iodine-catalyzed imine activation for three-component nucleophilic addition reactions

β-Amino ketones and α-amino nitriles were synthesized from silyl enol ethers and trimethylsilyl cyanides, via a three-component nucleophilic addition reaction with aromatic aldehydes and amines; the reaction was found to be significantly accelerated by molecular iodine under neutral conditions.