73407-30-4Relevant academic research and scientific papers
Design, synthesis, and pharmacological evaluation of pyridinic analogues of nimesulide as cyclooxygenase-2 selective inhibitors
Julémont, Fabien,De Leval, Xavier,Michaux, Catherine,Renard, Jean-Fran?ois,Winum, Jean-Yves,Montero, Jean-Louis,Damas, Jacques,Dogné, Jean-Michel,Pirotte, Bernard
, p. 6749 - 6759 (2007/10/03)
In this study, we report the synthesis and pharmacological evaluation of original pyridinic sulfonamides related to nimesulide, a cyclooxygenase-2 (COX-2) preferential inhibitor widely used as an anti-inflammatory agent. These original pyridinic derivativ
3-Aryloxy-substituted-aminopyridines and methods for their production
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, (2008/06/13)
3-Aryloxy-substituted-aminopyridines and salts thereof, which are useful as pharmacological agents, especially cognition activators, are disclosed. They can be produced by reacting a chloro-3-aryloxypyridine with a substituted amine, 3-bromo-substituted-aminopyridine with an alkali metal salt of a phenol compound or by deoxygenation of a 3-aryloxy-substituted-aminopyridine N-oxide.
