73441-51-7

Usage

InChI:InChI=1/C11H17N/c1-9(2)11-6-4-10(5-7-11)8-12-3/h4-7,9,12H,8H2,1-3H3

Upstream product

• 17972-10-0 (4-isopropyl-benzylidene)-methyl-amine 
• 73789-86-3 4-i-propylbenzyl bromide 
• 74-89-5 methylamine 
• 2051-18-5 4-isopropylbenzyl chloride 
• 122-03-2 (4-isopropylbenzaldehyde) 
• 6502-22-3 2-isopropylbenzaldehyde 

Downstream Products

• 100607-95-2 dichloro-acetic acid-[(4-isopropyl-benzyl)-methyl-amide] 
• 1187212-41-4 4-((4-isopropylbenzyl)methylamino)benzaldehyde 
• 110932-32-6 N-methyl-N-(4'-isopropylbenzyl)-1-(2-methylnaphthalene)methylamine 

Relevant academic research and scientific papers

AZETIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF METABOLIC AND INFLAMMATORY DISEASES

Compounds are disclosed that have a formula represented by the following: These compounds may be prepared as a pharmaceutical composition, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example inflammatory conditions, infectious diseases, autoimmune diseases, diseases involving impairment of immune cell functions, cardiometabolic diseases, and/or proliferative diseases.

NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS

The present invention relates to the novel compounds of the general formula (I), wherein the symbols are same as described in specification, their pharmaceutically acceptable salts, their tautomeric forms, their stereoisomers, pharmaceutical compositions containing them, to process and intermediates for the preparation of the above said compounds, having the utility of these compounds in medicine and to methods for their therapeutic use, and their use in the treatment of diabetes and related diseases.

β-lactam derivatives as inhibitors of human cytomegalovirus protease

The development of novel monobactam inhibitors of HCMV protease incorporating a carbon side chain at C-4 and a urea function at N-1 is described. Substitution with small groups at the C-3 position of the β- lactam ring gave an increase in enzymatic activity and in stability; however, a lack of selectivity against other serine proteases was noted. The use of both triand tetrasubstituted urea functionalities gave effective inhibitors of HCMV protease. Benzyl substitution of the urea moiety was beneficial, especially when strong electron-withdrawing groups where attached at the para position. Modest antiviral activity was found in a plaque reduction assay.