7355-22-8

Basic information

• Product Name: 5-BROMO-2,4-DIHYDROXYBENZOIC ACID
• Synonyms: LABOTEST-BB LT00454955;5-BROMO-2,4-DIHYDROXYBENZOIC ACID;5-BROMO-BETA-RESORCYLIC ACID;2 4-DIHYDROXY-5-BROMOBENZOIC ACID;Benzoic acid, 5-bromo-2,4-dihydroxy-;beta-Resorcylic acid, 5-bromo-;5-Bromo-§5-bromo-á-resorcylic acid
• CAS NO: 7355-22-8
• Molecular Formula: C₇H₅BrO₄
• Molecular Weight: 233.02
• EINECS: 230-881-9
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 7355-22-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 208-210°C
• Boiling Point: 436.7 °C at 760 mmHg
• Flash Point: 217.9 °C
• Appearance: /
• Density: 2.026 g/cm³
• Vapor Pressure: 2.13E-08mmHg at 25°C
• Refractive Index: 1.703
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.83±0.10(Predicted)
• BRN: 2967526
• CAS DataBase Reference: 5-BROMO-2,4-DIHYDROXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2,4-DIHYDROXYBENZOIC ACID(7355-22-8)
• EPA Substance Registry System: 5-BROMO-2,4-DIHYDROXYBENZOIC ACID(7355-22-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-36
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 7355-22-8(Hazardous Substances Data)

Usage

General Description

5-Bromo-2,4-dihydroxybenzoic acid is a synthetic organic compound belonging to the class of benzoic acids. It is a derivative of 2,4-dihydroxybenzoic acid, with a bromine atom attached to the 5th carbon atom. This chemical is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. It possesses antioxidant properties due to the presence of hydroxyl groups, and has been studied for its potential use in the development of anti-inflammatory and antimicrobial drugs. Additionally, 5-bromo-2,4-dihydroxybenzoic acid is also utilized as a reagent in various chemical reactions and as a standard in analytical chemistry.

InChI:InChI=1/C7H5BrO4/c8-4-1-3(7(11)12)5(9)2-6(4)10/h1-2,9-10H,(H,11,12)

Upstream product

• 89-86-1 4-hydroxysalicylic acid 
• 6626-15-9 4-Bromoresorcinol 
• 124-38-9 carbon dioxide 

Downstream Products

• 100116-14-1 5-bromo-2,4-dihydroxy-3-morpholinomethyl-benzoic acid 
• 99853-34-6 5-bromo-3-butyryl-2,4-dihydroxy-benzoic acid 
• 99853-33-5 5-bromo-4-butyryloxy-2-hydroxy-benzoic acid 
• 98437-41-3 5-bromo-2-hydroxy-4-methoxybenzoic acid 
• 17715-69-4 1-Bromo-2,4-dimethoxybenzene 
• 63604-94-4 2-bromo-5-methoxyphenol 
• 39503-51-0 2,4-Dimethoxy-5-bromobenzoic acid methyl ester 
• 102127-34-4 4-bromo-3-methoxyphenol 
• 912545-10-9 2,4-bis(benzyloxy)-5-bromobenzoic acid 
• 912545-14-3 benzyl 2,4-bis(benzyloxy)-5-bromobenzoate 
• 909871-20-1 5-bromo-2,4-bis(methoxymethoxy)benzoic acid methoxymethyl ester 

Relevant articles and documents

Kolbe-Schmitt type reaction under ambient conditions mediated by an organic base

The combined use of an organic base for resorcinols realized a Kolbe-Schmitt type reaction under ambient conditions. When resorcinols (3-hydroxyphenol derivatives) were treated with DBU under a carbon dioxide atmosphere, nucleophilic addition to carbon dioxide proceeded to afford the corresponding salicylic acid derivatives in high yields.

Phenyl 1, 2 - isoxazole or phenyl 1, 2 - pyrazole compound and use thereof (by machine translation)

The invention discloses the following formula of phenyl 1, 2 - different oxazole or 1, 2 - pyrazole compounds with use. Through the biological activity tests show that, the compound inhibiting heat shock protein 90 activity. Therefore, the invention phenyl 1, 2 - different oxazole or 1, 2 - pyrazole compounds can be used as a heat shock protein 90 inhibitor for the treatment of cancer. (by machine translation)

Simple and improved regioselective brominations of aromatic compounds using N-benzyl-N,N-dimethylanilinium peroxodisulfate in the presence of potassium bromide under mild reactions conditions

A simple, efficient, and mild method for the selective bromination of some activated aromatic compounds using N-benzyl-N,N-dimethylanilinium peroxodisulfate in the presence of potassium bromide in non-aqueous solution is reported. The results obtained revealed good to excellent selectivity between the ortho and para positions of phenols and methoxyarenes.