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Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-2-hydroxy-4-methoxybenzoic acid is used as a building block for the synthesis of pharmaceutical drugs. Its unique structure allows it to be a key component in the development of new chemical compounds with therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 5-Bromo-2-hydroxy-4-methoxybenzoic acid serves as a precursor in the synthesis of various agrochemical products. Its potential antifungal and antibacterial properties make it a valuable asset in the development of new pesticides and fungicides.
Used as a Reagent:
5-Bromo-2-hydroxy-4-methoxybenzoic acid is commonly used as a reagent in organic synthesis. Its versatility in chemical reactions makes it a popular choice for researchers and chemists working on the synthesis of new compounds.
Used as an Intermediate:
5-BROMO-2-HYDROXY-4-METHOXYBENZOIC ACID also serves as an intermediate in the synthesis of other organic compounds. Its presence in the reaction process can help facilitate the formation of desired products, making it an essential component in many chemical processes.

InChI:InChI=1/C8H7BrO4/c1-13-7-3-6(10)4(8(11)12)2-5(7)9/h2-3,10H,1H3,(H,11,12)

Upstream product

• 2237-36-7 4-methoxysalicylic acid 
• 7355-22-8 5-bromo-4-hydroxysalicylic acid 
• 77-78-1 dimethyl sulfate 
• 89-86-1 4-hydroxysalicylic acid 
• 91-52-1 2,4 dimethoxybenzoic acid 
• 32246-20-1 5-bromo-2,4-dimethoxybenzoic acid 

Downstream Products

• 6626-15-9 4-Bromoresorcinol 
• 102127-34-4 4-bromo-3-methoxyphenol 
• 108989-42-0 5-bromo-2-hydroxy-4-methoxy-benzoic acid anilide 
• 39503-52-1 methyl 5-bromo-2-hydroxy-4-methoxybenzoate 
• 1379779-22-2 C₈H₆BrNO₂ 
• 130890-81-2 5-bromo-4-methoxy-N-(1-benzyl-4-piperidinyl)salicylamide 

Relevant academic research and scientific papers

Big catkin willow acids compounds and medical use

The invention discloses a AMPK agonist activity with salicylic acid compound and its preparation method and medical use, it is the structural formula of the formula (I) compound of formula, its pharmaceutically acceptable salt or prodrug or solvate. The structure of the invention of formula (I) compound of formula activated AMPK, therefore can be used for preparing the prevention or treatment of AMPK mediated diseases.

Potential antipsychotic agents. 6. Synthesis and antidopaminergic properties of substituted N-(1-benzyl-4-piperidinyl)salicylamides and related compounds. QSAR based design of more active members

A number of substituted 2-methoxybenzamides, with and without 6-hydroxy groups, with 4-piperidinyl side-chains have been synthesized and evaluated for their antidopaminergic properties. The salicylamides were found to require a lipophilic N-substituent, like a benzyl group, for high affinity for the dopamine D-2 binding site in contrast to salicylamides with 2-pyrrolodinylmethyl side-chains. Furthermore, the influence of the aromatic substituents on the activity in the 2 series, ie 4-piperidinyl and 2-pyrrolidinylmethyl side-chains, was different. This was supported by a Hansch analysis, which could accomodate both phenolic and non-phenolic benzamides with 1-benzyl-4-piperidinyl side-chains. The activity is primarily dictated by electronic features rather than by steric and lipophilic properties. The QSAR equations were validated by the design and synthesis of a new 10-fold more active derivative. The 2 classes of benzamides with different side-chains are suggested to act on different binding sites or on different subtypes of the dopamine D-2 receptor.