73686-46-1

Basic information

• Product Name: Benzoic acid, 2-methyl-, 2-pyridinyl ester
• CAS NO: 73686-46-1
• Molecular Formula: C13H11NO2
• Molecular Weight: 213.236
• Mol File: 73686-46-1.mol

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-methyl-, 2-pyridinyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-methyl-, 2-pyridinyl ester(73686-46-1)
• EPA Substance Registry System: Benzoic acid, 2-methyl-, 2-pyridinyl ester(73686-46-1)

Safety Data

• Hazardous Substances Data: 73686-46-1(Hazardous Substances Data)

Upstream product

• 142-08-5 2-hydroxypyridin 
• 933-88-0 ortho-toluoyl chloride 
• 118-90-1 ortho-methylbenzoic acid 

Downstream Products

• 27582-42-9 (9H-Fluoren-2-yl)-o-tolyl-methanone 
• 15813-38-4 phenyl 2-methylbenzoate 
• 23597-25-3 p-tolyl 2-methylbenzoate 
• 500285-59-6 2-methyl-benzoic acid-(4-chloro-phenyl ester) 
• 306743-67-9 4-acetophenyl 2-methylbenzoate 
• 74738-56-0 4-nitrophenyl 2-methylbenzoate 
• 89127-43-5 4-methoxyphenyl-o-toluate 
• 73178-44-6 1-(2-methylphenyl)-1-pentanol 
• 131-58-8 2-Methylbenzophenone 

Relevant articles and documents

Heterogeneous Suzuki-Miyaura coupling of heteroaryl ester: Via chemoselective C(acyl)-O bond activation

A site-selective supported palladium nanoparticle catalyzed Suzuki-Miyaura cross-coupling reaction with heteroaryl esters and arylboronic acids as coupling partners was developed. This methodology provides a heterogeneous catalytic route for aryl ketone formation via C(acyl)-O bond activation of esters by successful suppression of the undesired decarbonylation phenomenon. The catalyst can be reused and shows high activity after eight cycles. The XPS analysis of the catalyst before and after the reaction suggested that the reaction might be performed via a Pd0/PdII catalytic cycle that began with Pd0.

Transesterification of (hetero)aryl esters with phenols by an Earth-abundant metal catalyst

Readily available and inexpensive Earth-abundant alkali metal species are used as efficient catalysts for the transesterification of aryl or heteroaryl esters with phenols which is a challenging and underdeveloped transformation. The simple conditions and the use of heterogeneous alkali metal catalyst make this protocol very environmentally friendly and practical. This reaction fills in the missing part in transesterification reaction of phenols and provides an efficient approach to aryl esters, which are widely used in the synthetic and pharmaceutical industry.

A new ketone synthesis by palladium-catalyzed cross-coupling reactions of esters with organoboron compounds

(Chemical Equation Presented) The palladium-catalyzed coupling reaction of 2-pyridyl esters with organoboron compounds is described. The reaction is compatible with various functional groups and proceeds under mild reaction conditions. The coordination of the nitrogen atom to Pd is a key step for efficient reaction.