15813-38-4

Basic information

• Product Name: Benzoic acid, 2-methyl-, phenyl ester
• Synonyms: o-Toluic acid,phenyl ester;Benzoic acid,2-methyl-,phenyl ester;o-methylbenzoic acid phenyl ester;o-Tolylsaeurephenylester;phenyl-o-toluate;2-Methylbenzoesaeure-phenylester;2-methyl-benzoic acid phenyl ester
• CAS NO: 15813-38-4
• Molecular Formula: C14H12O2
• Molecular Weight: 212.248
• Mol File: 15813-38-4.mol
• Article Data: 33

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-methyl-, phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-methyl-, phenyl ester(15813-38-4)
• EPA Substance Registry System: Benzoic acid, 2-methyl-, phenyl ester(15813-38-4)

Safety Data

• Hazardous Substances Data: 15813-38-4(Hazardous Substances Data)

Upstream product

• 118-90-1 ortho-methylbenzoic acid 
• 108-95-2 phenol 
• 933-88-0 ortho-toluoyl chloride 
• 615-37-2 ortho-methylphenyl iodide 
• 201230-82-2 carbon monoxide 
• 2996-92-1 phenyl trimethylsiloxane 
• 98-80-6 phenylboronic acid 
• 98-88-4 benzoyl chloride 
• 95-48-7 ortho-cresol 
• 64-18-6 formic acid 
• 67-66-3 chloroform 
• 73686-46-1 2-methylbenzoic acid 2-pyridinyl ester 
• 87-24-1 ethyl 2-methylbenzoate 
• 50978-45-5 3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide 

Downstream Products

• 118-90-1 ortho-methylbenzoic acid 
• 108-95-2 phenol 
• 80791-90-8 N-benzoyl-2-methylbenzamide 
• 670221-37-1 (4-benzoyl-2-methyl-phenoxy)-acetic acid ethyl ester 
• 670221-34-8 2-(4-benzoyl-2-methylphenoxy)acetohydrazide 
• 5326-42-1 3-methyl-4-hydroxybenzophenone 
• 55814-36-3 α-(p-anisidino)-o-tolualdehyde 
• 1140-16-5 (2-methylphenyl)(4-methylphenyl)methanone 

Relevant articles and documents

Synthesis, xanthine oxidase inhibition, and antioxidant screening of benzophenone tagged thiazolidinone analogs

A series of novel 2-(diaryl methanone)-N-(4-oxo-2-phenyl-thiazolidin-3-yl)- acetamides were synthesized by various Schiff bases of (4-benzoyl-phenoxy)-aceto hydrazide with thioglycolic acid. The structures of the newly synthesized compounds were confirmed

Hydrogen-bond-assisted transition-metal-free catalytic transformation of amides to esters

The amide C-N cleavage has drawn a broad interest in synthetic chemistry, biological process and pharmaceutical industry. Transition-metal, luxury ligand or excess base were always vital to the transformation. Here, we developed a transition-metal-free hydrogen-bond-assisted esterification of amides with only catalytic amount of base. The proposed crucial role of hydrogen bonding for assisting esterification was supported by control experiments, density functional theory (DFT) calculations and kinetic studies. Besides broad substrate scopes and excellent functional groups tolerance, this base-catalyzed protocol complements the conventional transition-metal-catalyzed esterification of amides and provides a new pathway to catalytic cleavage of amide C-N bonds for organic synthesis and pharmaceutical industry. [Figure not available: see fulltext.]

PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS

The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The modular synthesis of tetracyclines and tetracycline analogs described provides an efficient and enantioselective route to a variety of tetracycline analogs and polycyclines previously inaccessible via earlier tetra-cycline syntheses and semi-synthetic methods. These analogs may be used as anti-microbial agents or anti-pro liferative agents in the treatment of diseases of humans or other animals.