73747-40-7

Basic information

• Product Name: 1-Benzyl-2-hydroxyethylcarbamic acid benzyl ester
• Synonyms: 1-Benzyl-2-hydroxyethylcarbamic acid benzyl ester;N-(1-Benzyl-2-hydroxyethyl)carbamic acid benzyl ester
• CAS NO: 73747-40-7
• Molecular Formula: C₁₇H₁₉NO₃
• Molecular Weight: 285.34
• Mol File: 73747-40-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Benzyl-2-hydroxyethylcarbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl-2-hydroxyethylcarbamic acid benzyl ester(73747-40-7)
• EPA Substance Registry System: 1-Benzyl-2-hydroxyethylcarbamic acid benzyl ester(73747-40-7)

Safety Data

• Hazardous Substances Data: 73747-40-7(Hazardous Substances Data)

Usage

Chemical class

Carbamic acid benzyl ester

Derivative of

Carbamic acid

Contains groups

Benzyl and hydroxyethyl

Common use

Organic synthesis and pharmaceutical research

Specific application

Development of new drugs

Potential applications

Pesticide and herbicide production

Biological activities

May exhibit certain biological activities

Therapeutic uses

Potential therapeutic uses

Importance

Important compound for further exploration and study

Upstream product

• 3426-71-9 Benzyl N-hydroxycarbamate 
• 300-57-2 allylbenzene 
• 1262306-22-8 benzyloxycarbonylamino-4-chlorobenzoate 
• 501-53-1 benzyl chloroformate 
• 1217341-14-4 C₁₈H₂₃NO₂ 
• 1084820-37-0 1,1-dimethoxy-3-phenylpropan-2-one oxime 
• 59830-60-3 N-benzyloxycarbonyl-2-amino-3-phenylpropionaldehyde 
• 59830-61-4 benzyl 1-benzyl-2,2-dimethoxyethylcarbamate 
• 55707-43-2 1-benzyl-2,2-dimethoxyethylamine 
• 100-46-9 benzylamine 
• 3588-57-6 Z-DL-Phe-OH 
• 62750-39-4 1-<(Benzyl-carbobenzoxyamino)-acetyl>-imidazol 
• 121335-13-5 2-Benzyloxycarbonylamino-3-phenyl-propionic acid 6-nitro-benzotriazol-1-yl ester 

Downstream Products

• 59830-60-3 N-benzyloxycarbonyl-2-amino-3-phenylpropionaldehyde 
• 1235475-84-9 C₁₉H₂₁NO₄ 
• 1101103-75-6 (R)-2-benzyloxycarbonylamino-3-phenylpropyl acetate 
• 1227627-68-0 2-(benzyloxycarbonylamino)-3-phenylpropyl acetate 
• 105507-42-4 (+/-)-3-[(Benzyloxycarbonyl)amino]-4-phenylbutan-2-one 
• 249296-51-3 (+/-)-3-[(Benzyloxycarbonyl)amino]-4-phenylbutan-2-ol 

Relevant articles and documents

A rapid and efficient one-pot method for the reduction of N-protected α-amino acids to chiral α-amino aldehydes using CDI/DIBAL-H

N-Protected amino acids can be easily converted into chiral α-amino aldehydes in a one-pot reaction by activation with CDI followed by reduction with DIBAL-H. This method delivers Boc-, Cbz- and Fmoc-protected amino aldehydes from proteinogenic amino acids in very good isolated yields and complete stereointegrity.

Alkyl 4-chlorobenzoyloxycarbamates as highly effective nitrogen source reagents for the base-free, intermolecular aminohydroxylation reaction

Ethyl-(7), benzyl-(8), tert-butyl-(9), and fluorenylmethyl-4- chlorobenzoyloxycarbamates (10) have been prepared as storable and easy-to-prepare nitrogen sources for use in the intermolecular Sharpless aminohydroxylation reaction and its asymmetric variant. These reagents were found to be effective under base-free reaction conditions. The scope and limitations of these methods have been explored using a variety of alkenes, among which, trans-cinnamates, in particular, proved to be good substrates.

Facile Reduction of Intermediates from Carboxylic Acids and 6-Nitro-1-(2-nitrophenylsulfonyloxy)benzotriazole with Sodium Borohydride to Alcohols

Reduction of activated intermediates derived from 6-nitro-1-(2-nitrophenylsulfonyloxy)-benzotriazole and carboxylic acids with sodium borohydride readily afforded the corresponding alcohols in 71-93percent yields.Keywords: 6-nitro-1-(2-nitrophenylsulfonyloxy)benzotriazole; 1-acyloxy-6-nitrobenzotriazole; 3-acyl-6-nitrobenzotriazole 1-oxide; sodium borohydride reduction; alcohol synthesis