738604-46-1

Upstream product

• 110-00-9 furan 
• 114671-83-9 1-(t-butyldiphenylsilyloxy)-3-iodopropane 
• 26908-23-6 3-furan-2-yl-propan-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 10031-90-0 ethyl 3-(furan-2-yl)propanoate 

Downstream Products

• 738604-49-4 5-[3-(tert-butyldiphenylsilyloxy)propyl]-5-methyloxy-5H-furan-2-one 
• 1027994-01-9 C₃₃H₄₈O₃Si₂ 
• 944382-67-6 5-(3'-tert-butyldiphenylsilyloxy-propan-1'-yl)-2-(4-hydroxy-but-1'-en-1'-yl)-furan 
• 1035420-77-9 C₂₄H₃₂O₅Si 
• 1257242-79-7 6-[3-(tert-butyldiphenylsilyloxy)propyl]pyridazin-3(2H)-one 
• 1257242-82-2 6-[3-(tert-butyldiphenylsilyloxy)propyl]-2-methylpyridazin-3(2H)-one 
• 1257242-85-5 2-benzyl-6-[3-(tert-butyldiphenylsilyloxy)propyl]pyridazin-3(2H)-one 
• 1257242-93-5 2-benzyl-6-(3-hydroxypropyl)pyridazin-3(2H)-one 

Relevant academic research and scientific papers

The furan approach to oxacycles. Part 3: Stereoselective synthesis of 2,3-disubstituted tetrahydropyrans

Commercially available furan 1 was converted to 2,3-trans and 2,3-cis-disubstituted tetrahydropyrans 2 and 3 using a highly efficient route to oxacycles, based on the oxidation of the furan ring with singlet oxygen. Tetrahydropyrans 2 and 3 could be easil

Cyclopentanone derivatives, method of synthesis and uses thereof

The present invention relates to cyclopentanone derivatives of formula (I), their method of synthesis and uses thereof. Concretely, the compounds disclosed have proved to be inhibitors of glycogen synthase kinase 3β, GSK-3 β, which is known to be involved in different disease and conditions, such as Alzheimer's disease or non-insulin dependent diabetes mellitus. The present invention also relates to pharmaceutical compositions comprising the same. Further, the present invention is directed to the use of the compounds in the manufacture of a medicament for the treatment and/or prevention of a GSK-3 mediated disease or condition.

Cascade radical-mediated cyclisations with conjugated ynone electrophores. An approach to the synthesis of steroids and other novel ring-fused polycyclic carbocycles

A cascade radical-mediated Diels-Alder reaction with the iododienynone 16b produced the tricyclic ketone 17 (22%). By contrast, treatment of the substituted furans 36 and 47 with Bu3SnH-AIBN, instead led to the tetracycles 44 and 58 respectivel

The furan approach to oxacycles: Synthesis of medium-size 2,3-disubstituted oxacycles

We describe an efficient new approach for the synthesis of medium-size oxacycles that is based on the oxidation of a furan ring with singlet oxygen followed by an intramolecular Michael addition. This present study enlarges the scope of the furan approach strategy for the synthesis of oxepanes.