738604-49-4

Upstream product

• 10031-90-0 ethyl 3-(furan-2-yl)propanoate 
• 1035420-77-9 C₂₄H₃₂O₅Si 
• 114671-83-9 1-(t-butyldiphenylsilyloxy)-3-iodopropane 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 26908-23-6 3-furan-2-yl-propan-1-ol 
• 67-56-1 methanol 
• 738604-46-1 2-(tert-butyldiphenylsilyloxy-propan-1'-yl)-furan 

Downstream Products

• 1014987-81-5 C₂₅H₃₂N₂O₄Si 

Relevant academic research and scientific papers

New pyridazinone derivatives with vasorelaxant and platelet antiaggregatory activities

New 6-substituted and 2,6-disubstituted pyridazinone derivatives were obtained starting from easily accessible alkyl furans by using oxidation with singlet oxygen to give 4-methoxy or 4-hydroxybutenolides, key intermediates of this synthetic strategy. The

Cyclopentanone derivatives, method of synthesis and uses thereof

The present invention relates to cyclopentanone derivatives of formula (I), their method of synthesis and uses thereof. Concretely, the compounds disclosed have proved to be inhibitors of glycogen synthase kinase 3β, GSK-3 β, which is known to be involved in different disease and conditions, such as Alzheimer's disease or non-insulin dependent diabetes mellitus. The present invention also relates to pharmaceutical compositions comprising the same. Further, the present invention is directed to the use of the compounds in the manufacture of a medicament for the treatment and/or prevention of a GSK-3 mediated disease or condition.

The furan approach to oxacycles. Part 3: Stereoselective synthesis of 2,3-disubstituted tetrahydropyrans

Commercially available furan 1 was converted to 2,3-trans and 2,3-cis-disubstituted tetrahydropyrans 2 and 3 using a highly efficient route to oxacycles, based on the oxidation of the furan ring with singlet oxygen. Tetrahydropyrans 2 and 3 could be easil

The furan approach to oxacycles: Synthesis of medium-size 2,3-disubstituted oxacycles

We describe an efficient new approach for the synthesis of medium-size oxacycles that is based on the oxidation of a furan ring with singlet oxygen followed by an intramolecular Michael addition. This present study enlarges the scope of the furan approach strategy for the synthesis of oxepanes.