739-26-4Relevant academic research and scientific papers
NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF
-
Page/Page column 87; 88, (2015/02/02)
Described herein are neuroactive steroids of the Formula (I): (Formula (I)) or a pharmaceutically acceptable salt thereof; wherein R1a and R1b are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.
METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID
-
, (2013/06/05)
Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxy-steroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID
-
Page/Page column 68, (2011/07/07)
Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxysteroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
SYNTHESIS OF 11-HYDROXYLATED ANDROSTANE DERIVATIVES
Fajkos, Jan,Joska, Jiri
, p. 1845 - 1849 (2007/10/02)
Reaction conditions for selective reductions of 3- and 17-oxo groups are described and applied to syntheses of 11-hydroxylated derivatives.
