73978-74-2

Usage

Uses

Used in Pharmaceutical Industry:
6-amino-2,4-dimethoxy-5-nitropyrimidine is used as a building block for the synthesis of various drugs. Its unique chemical structure allows it to be a versatile component in the development of new pharmaceutical compounds.
Used in Agrochemical Industry:
6-amino-2,4-dimethoxy-5-nitropyrimidine is used as a building block for the synthesis of herbicides. Its properties make it a valuable component in the creation of effective and targeted weed control agents.
Used in Antitumor Applications:
6-amino-2,4-dimethoxy-5-nitropyrimidine is used as a potential antitumor agent. Its chemical structure may contribute to the development of new treatments for cancer, offering hope for improved therapies in the future.
Used in Dye and Pigment Production:
6-amino-2,4-dimethoxy-5-nitropyrimidine is used in the production of dyes and pigments. Its yellow crystalline form and chemical properties make it suitable for use in various coloring applications across different industries.
Used in Medicinal Chemistry Research:
6-amino-2,4-dimethoxy-5-nitropyrimidine is used in research for its potential role in the treatment of various diseases. Its unique structure and properties make it an important compound for exploring new therapeutic avenues and advancing medical knowledge.

InChI:InChI=1/C6H8N4O4/c1-13-5-3(10(11)12)4(7)8-6(9-5)14-2/h1-2H3,(H2,7,8,9)

Upstream product

• 31221-68-8 2,6-dichloro-5-nitropyrimidin-4-amine 
• 124-41-4 sodium methylate 
• 3289-50-7 2,6-dimethoxypyrimidin-4-amine 
• 73978-73-1 4-amino-2,6-dimethoxy-5-nitrosopyrimidine 
• 6320-15-6 6-chloro-2,4-dimethoxypyrimidine 
• 60331-03-5 4-chloro-2,6-dimethoxy-5-nitropyrimidine 

Downstream Products

• 5327-19-5 2,6-dimethoxy-7(9)H-purine 
• 133185-44-1 5,6-Diamino-2,4-dimethoxypyrimidine 
• 73978-76-4 2,4-Dimethoxy-5-nitro-6-<(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)amino>pyrimidin 
• 73978-75-3 2,4-Dimethoxy-5-nitro-6-<(2,3,5-tri-O-benzoyl-α-D-ribofuranosyl)amino>pyrimidin 
• 73978-84-4 4-methoxy-2-oxo-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-7-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)-1,2-dihydropteridin 
• 73978-83-3 2,4-Dimethoxy-7-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)pteridin 
• 73978-86-6 2,4-Dimethoxy-6-methyl-7-oxo-7,8-dihydropteridin 
• 73978-85-5 2,4-Dimethoxy-7-oxo-7,8-dihydropteridin 

Relevant academic research and scientific papers

Hydrogen bonding in nitroaniline analogues: Hydrogen-bonded sheets in 2-amino-4,6-dimethoxy-5-nitropyrimidine and π-stacked hydrogen-bonded sheets in 4-amino-2,6-dimethoxy-5-nitropyrimidine

In 2-amino-4,6-dimethoxy-5-nitropyrimidine, C6H8N4O4, the molecules are linked by one N-H...N and one N-H...O hydrogen bond to form sheets built from alternating R22(8) and R66(32) rings. In isomeric 4-amino-2,6-dimethoxy-5-nitropyrimidine, C6H8N4O4, which crystallizes with Z′ = 2 in P1macr;, the two independent molecules are linked into a dimer by two independent N-H...N hydrogen bonds. These dimers are linked into sheets by a combination of two-centre C-H...O and three-centre C-H...(O)2 hydrogen bonds, and the sheets are further linked by two independent aromatic π-π-stacking interactions to form a three-dimensional structure.

Synthesis and cyclization of novel lumazine - Enediyne chimeras

Lumazine derivatives (6-8), appended with ethynyl groups in positions 7 and 8, were synthesized and examined for their ability to undergo Bergman cyclization. Oxo compound (7) was found to give good yields of Bergman cyclization products (? 37 %), whereas the analogues (6) and (8) did not cyclize as efficiently or gave no identifiable cyclization products.

Herbicidal pyridyl sulfonamides

Certain N-[(pyridyl or pyrimidyl)aminocarbonyl]arylsulfonamides, such as the compound methyl 2-[[N-(3-cyano-4,6-dimethylpyridin-2-yl)aminocarbonyl]aminosulfonyl]benzoate, possess herbicidal activity.

Lower alkyl 2-[[N-(3-cyano-pyridin-2-yl)aminocarbonyl]aminosulphonyl]benzoate derivatives having herbicidal activity

Certain N-[(pyridyl or pyrimidyl)aminocarbonyl]arylsulfonamides, such as the compound methyl 2-[[N-(3-cyano-4,6-dimethylpyridin-2-yl)aminocarbonyl]aminosulfonyl]benzoate, possess herbicidal activity.

Nucleosides, XXXIII. Synthesis of 7-Oxo-8-β-D-ribofuranosyl-7,8-dihydrolumazine and its 6-Methyl Derivative

The synthesis of 7-oxo-8-β-D-ribofuranosyl-7,8-dihydrolumazine (26) and its 6-methyl derivative (28) has been achieved by a ribosylation reaction of 2,4-bis(benzyloxy)- (18) and 2,4-bis(benzyloxy)-6-methyl-7-oxo-7,8-dihydropteridine (19), respectively, un