73991-97-6Relevant academic research and scientific papers
Rhodium-catalyzed asymmetric synthesis of β-branched esters from allylic amines
Laffoon, Summer D.,Wu, Zhao,Hull, Kami L.
supporting information, p. 7814 - 7817 (2018/07/25)
Allylic amines are converted to chiral, β-branched esters under rhodium catalysis in the presence of alcohol nucleophiles. Allylic amines with aliphatic and aromatic vinylic substituents are converted to ester products with excellent enantioselectivities in all cases. Several alcohol nucleophiles have been utilized in the reaction including 1° and 2° derivatives.
A highly efficient total synthesis of (R)-(+)-muscopyridine by intramolecular [4+2] cycloaddition of bisketene
Suwa, Kie,Morie, Yasuko,Suzuki, Yumiko,Ikeda, Kiyoshi,Sato, Masayuki
, p. 1510 - 1513 (2008/09/19)
A highly efficient total synthesis of (R)-(+)-muscopyridine 1 has been accomplished in 12 steps with 40% overall yield. A highlight of the synthesis is the intramolecular [4+2] cycloaddition of bisketene to afford a bridged pyrone and ring transformation
Chiral Lewis acid-catalyzed enantioselective intramolecular carbonyl ene reactions of unsaturated α-keto esters
Yang, Dan,Yang, Min,Zhu, Nian-Yong
, p. 3749 - 3752 (2007/10/03)
(Matrix Presented) Chiral Lewis acid-promoted highly enantioselective intramolecular carbonyl ene reactions of unsaturated α-keto esters have been investigated. In the presence of chiral Lewis acids such as [Sc((R,R)-Ph-pybox)](OTf)3 and [Cu((S
