74007-56-0

Basic information

• Product Name: 2-(4-Chloro-phenyl)-3,3-dimethoxy-1-phenyl-propan-1-one
• CAS NO: 74007-56-0
• Molecular Weight: 304.773
• Mol File: 74007-56-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-Chloro-phenyl)-3,3-dimethoxy-1-phenyl-propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Chloro-phenyl)-3,3-dimethoxy-1-phenyl-propan-1-one(74007-56-0)
• EPA Substance Registry System: 2-(4-Chloro-phenyl)-3,3-dimethoxy-1-phenyl-propan-1-one(74007-56-0)

Safety Data

• Hazardous Substances Data: 74007-56-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 956-04-7 3-(4-chlorophenyl)-1-phenylprop-2-en-1-one 
• 24721-26-4 4-chlorochalcone 
• 149-73-5 trimethyl orthoformate 
• 956215-95-5 3-(4-chlorophenyl)-1-phenyl-2,3-ditosyloxypropanone 

Relevant articles and documents

The chemistry of α,β-ditosyloxyketones: Novel routes for the synthesis of desoxybenzoins and α-aryl-β-ketoaldehyde dimethylacetals from α,β-chalcone ditosylates

The reaction of α,β-chalcone ditosylates 3 with potassium hydroxide in suitable conditions leads to 1,2-aryl shift and carbon-carbon bond cleavage, thereby providing a novel route for the synthesis of 1,2-diarylethan-1-ones 4 and 1,2-diaryl-3,3-dimethoxy propan-1-ones 5. Georg Thieme Verlag Stuttgart.

Thallium in Organic Synthesis. 57. Reaction of Chalcones and Chalcone Ketals with Thallium(III) Trinitrate

Treatment of chalcones (ArCH=CHCOAr') with thallium(III) trinitrate (TTN) in acidic methanol or in trimethyl orthoformate (TMOF) gives 3,3-dimethoxy-1,2-diarylpropan-1-ones (oxythallation, Ar rearrangement) and/or methyl 2,3-diaryl-3-methoxypropanoates (in situ ketal formation, oxythallation, Ar' rearrangement).The effect of substituents on Ar and Ar' on the ratio of the above rearrangement products has been examined.