740844-68-2

Basic information

• Product Name: 2-hydroxy-3-(4-nitro-phenyl)-propionic acid ethyl ester
• Synonyms: 2-hydroxy-3-(4-nitro-phenyl)-propionic acid ethyl ester
• CAS NO: 740844-68-2
• Molecular Weight: 239.228
• Mol File: 740844-68-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-3-(4-nitro-phenyl)-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-3-(4-nitro-phenyl)-propionic acid ethyl ester(740844-68-2)
• EPA Substance Registry System: 2-hydroxy-3-(4-nitro-phenyl)-propionic acid ethyl ester(740844-68-2)

Safety Data

• Hazardous Substances Data: 740844-68-2(Hazardous Substances Data)

Upstream product

• 924-44-7 glyoxylic acid ethyl ester 
• 100-14-1 4-nitrobenzyl chloride 
• 55895-91-5 ethyl 2-amino-3-(4-nitrophenyl) propanoate 

Relevant articles and documents

Nitrobenzylation of α-carbonyl ester derivatives using TDAE approach

A series of 2-hydroxy-propionic acid ethyl ester derivatives was prepared in good yields by reaction of o- and p-nitrobenzyl chlorides (1, 8) with various α-carbonyl esters in presence of tetrakis(dimethylamino)ethylene (TDAE). This reaction was generalized to α-ketolactam and α-ketomalonate.