740844-68-2Relevant academic research and scientific papers
Nitrobenzylation of α-carbonyl ester derivatives using TDAE approach
Giuglio-Tonolo, Gamal,Terme, Thierry,Médebielle, Maurice,Vanelle, Patrice
, p. 5121 - 5124 (2007/10/03)
A series of 2-hydroxy-propionic acid ethyl ester derivatives was prepared in good yields by reaction of o- and p-nitrobenzyl chlorides (1, 8) with various α-carbonyl esters in presence of tetrakis(dimethylamino)ethylene (TDAE). This reaction was generalized to α-ketolactam and α-ketomalonate.
Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
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Page 22, (2008/06/13)
The present invention relates to novel antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds of formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.
