741-76-4

Upstream product

• 110-91-8 morpholine 
• 727-62-8 2-chloro-3-phenylquinazoline-4-(3H)-one 
• 31162-13-7 2-azidobenzoic acid 
• 103-71-9 phenyl isocyanate 
• 622403-42-3 1-phenyl-3-(2-ethoxycarbonylphenyl) carbodiimide 
• 32045-49-1 ethyl-o-aminobenzoate hydrochloride 
• 118-92-3 anthranilic acid 
• 1218906-34-3 N-(2-iodophenyl)-N'-phenyldicarbodiimide 
• 13939-06-5 molybdenum hexacarbonyl 
• 603-23-6 3-phenyl-2,4-(1H,3H)-quinazolinedione 

Relevant academic research and scientific papers

Molybdenum-mediated synthesis of quinazolin-4(3H)-ones via cyclocarbonylation using microwave irradiation

A new, efficient and practical synthesis of quinazolin-4(3H)-ones is reported via molybdenum-mediated cyclocarbonylation using microwave irradiation. These methods allow access to a wide range of quinazolin-4(3H)-ones in reasonable yields without the need for gaseous carbon monoxide and palladium catalysts. A range of reactions illustrating the wide scope of this chemistry was carried out and all proceeded in reasonable yields.

A facile synthesis of 2-amino-3H-quinazolin-4-ones with tandem aza- Wittig reaction

2-Amino-3H-quinazolin-4-ones 8 were prepared from tandem aza-Wittig reaction of iminophosphorane 5 with aromatic isocyanate and nucleaphilic reagent HY in mild condition.

Solid-phase synthesis of 3H-Quinazolin-4-ones based on an aza Wittig-mediated annulation strategy

Aza Wittig-mediated annulation provides a highly efficient and straightforward strategy for the parallel synthesis of 3H-quinazolin-4-ones on solid support. The products were recovered in good yields and exhibited excellent purities.

Synthesis of Some Fused-ring Derivatives from 4(3H)-Quinazolone

A few more well-defined mesoionic thiazoloquinazolones have been synthesized and their properties recorded.Attempts to build-up analogous fused-ring mesoionic systems via 2-chloro-3-phenyl-4-quinazolone have not been successful.Several new triazolo