74152-12-8

Upstream product

• 622-51-5 p-tolylurea 
• 123-54-6 acetylacetone 
• 74152-07-1 4,6-Dimethyl-3-p-tolyl-3,4-dihydro-1H-pyrimidin-2-one 
• 107190-89-6 4-(3-ethoxypropyl)-6-methyl-1-p-tolylpyrimidin-2(1H)-one 

Downstream Products

• 80426-66-0 4,6-Dimethyl-1-p-tolyl-1H-pyrimidine-2-thione 
• 74360-01-3 3,4,5,6-tetrahydro-4,6-dimethyl-(p-tolyl)pyrimidin-2(1H)-one 
• 74830-22-1 3-p-tolyl-4,6-dimethyl-2-oxo-1,3-diazabicyclo<2.2.0>hex-5-ene 
• 10199-63-0 1-(3,5-dimethyl-1H-pyrazol-1-yl)ethanone 
• 300-87-8 3,5-dimethyl-1,2-oxazole 
• 136954-70-6 isopropyl <4-p-(tolylimino)-2-pentenyl>carbamate 
• 77942-45-1 4,4,6-trimethyl-1-p-tolyl-3,4-dihydropyrimidin-2(1H)-one 
• 77942-44-0 4,6,6-trimethyl-1-p-tolyl-3,6-dihydropyrimidin-2(1H)-one 

Relevant academic research and scientific papers

Crystal engineering of neutral N-arylpyrimidinones and their HCI and HNO3 adducts with a C-H···O supramolecular synthon. Implications for non-linear optics

In a previous crystallographic study of some N-arylpyrimidinones 1, we noted that: (1) C-H···O hydrogen bonds connect molecules in a linear array; (2) the charge transfer axis of the chromophore is aligned with the main symmetry operator of point groups 2

Photochemistry of Pyrimidin-2(1H)-ones: Intramolecular γ-Hydrogen Abstraction by the Nitrogen of the Imino Group

Irradiation of 1-aryl-4-propyl- (1a) and 1-aryl-4-(3-ethoxypropyl)-6-methylpyrimidin-2(1H)-ones (1b-d) gave the photoelimination products, 1-aryl-4,6-dimethylpyrimidin-2(1H)-ones (2a-d), via intramolecular γ-hydrogen atom abstraction of the excited imino nitrogen of the starting pyrimidin-2(1H)-one (1), in addition to the 1,3-diazabicyclohex-5-en-2-ones (3a-d).The pyrimidin-2(1H)-ones (1f) and (1h), which have no γ-hydrogens at the C-4 position, underwent photochemical electrocyclization to give the 1,3-diazabicyclohex-5-en-2-ones (3f) and (3h) as the sole products.

FACILE OXIDATION OF 2-OXO-1,4,6-TRISUBSTITUTED 1,2,3,6-TETRAHYDROPYRIMIDINES WITH CHLORANIL

2-Oxo-1,4,6-trisubstituted 1,2,3,6-tetrahydropyrimidines (1a-1h) were easily oxidized with 2,3,5,6-tetrachloro-1,4-benzoquinone (chloranil) to afford the corresponding 1,4,6-trisubstituted 2(1H)-pyrimidones (2) in good yields.