741693-79-8 Usage
Chemical Properties
Pale Brown Solid
Uses
Different sources of media describe the Uses of 741693-79-8 differently. You can refer to the following data:
1. A metabolite of Duloxetine.
2. A metabolite of Duloxetine
Check Digit Verification of cas no
The CAS Registry Mumber 741693-79-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,1,6,9 and 3 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 741693-79:
(8*7)+(7*4)+(6*1)+(5*6)+(4*9)+(3*3)+(2*7)+(1*9)=188
188 % 10 = 8
So 741693-79-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H21NO3S/c1-20-11-10-16(18-7-4-12-24-18)23-15-6-3-5-14-13(15)8-9-17(22-2)19(14)21/h3-9,12,16,20-21H,10-11H2,1-2H3/t16-/m0/s1
741693-79-8Relevant articles and documents
Synthesis and biological activity of some known and putative duloxetine metabolites
Kuo,Gillespie,Kulanthaivel,Lantz,Ma,Nelson,Threlkeld,Wheeler,Yi,Zmijewski
, p. 3481 - 3486 (2007/10/03)
Several putative phase I duloxetine metabolites, 4-hydroxy-, 5-hydroxy-, 6-hydroxy-, 5-hydroxy-6-methoxy-, 6-hydroxy-5-methoxy-, 5,6-dihydroxy-, and 4,6-dihydroxyduloxetine were synthesized, and their phase II metabolite as glucuronide or sulfate conjugates were also synthesized. Their in vitro binding activities were compared to that of parent compound duloxetine.