86-97-5 Usage
Description
5-AMINO-2-NAPHTHOL is an organic compound that serves as a crucial building block in the synthesis of various chemical compounds. It is characterized by the presence of an amino group attached to the 5-position and a hydroxyl group at the 2-position of the naphthalene ring. This unique structure endows it with versatile chemical properties, making it a valuable intermediate in organic synthesis.
Uses
Used in Pharmaceutical Industry:
5-AMINO-2-NAPHTHOL is used as a key intermediate in the synthesis of 6-amino-substituted benzo[c]phenanthridine derivatives. These derivatives possess significant biological activities and are employed as therapeutic agents in the treatment of various diseases.
Used in Biochemical Research:
5-AMINO-2-NAPHTHOL is used as a building block for the synthesis of affinity ligands targeting HIV-1 integrase. These ligands are essential tools in biochemical research for studying the mechanisms of action and developing potential inhibitors against HIV-1 integrase, a crucial enzyme in the life cycle of the human immunodeficiency virus.
Check Digit Verification of cas no
The CAS Registry Mumber 86-97-5 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 6 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 86-97:
(4*8)+(3*6)+(2*9)+(1*7)=75
75 % 10 = 5
So 86-97-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H9NO/c11-10-3-1-2-7-6-8(12)4-5-9(7)10/h1-6,12H,11H2
86-97-5Relevant articles and documents
Synthesis of Substituted Anilines from Cyclohexanones Using Pd/C-Ethylene System and Its Application to Indole Synthesis
Maeda, Katsumi,Matsubara, Ryosuke,Hayashi, Masahiko
supporting information, p. 1530 - 1534 (2021/03/08)
The synthesis of anilines and indoles from cyclohexanones using a Pd/C-ethylene system is reported. A simple combination of NH4OAc and K2CO3 under nonaerobic conditions was found to be the most suitable to perform this reaction. Hydrogen transfer between cyclohexanone and ethylene generates the desired products. The reaction tolerates a variety of substitutions on the starting cyclohexanones.