74185-58-3Relevant articles and documents
Method of coupling, and the coupling method using the aromatic group-substituted heterocyclic compound
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Paragraph 0292-0297; 0299, (2020/09/17)
Provided is an easy method (coupling method) capable of easily synthesizing a compound group in which aromatic molecules and aromatic molecules are coupled, a compound group in which aromatic molecules and alkene molecules are coupled, and the like without producing halogen waste and without the need to use scarce and expensive palladium. A compound (A) shown by general formula (A): Ar-H and a compound (B1) shown by general formula (B1): RaOCO-Ar', a compound (B2) shown by general formula (B2): RbCH=C(Ar")2, or a compound (B3) shown by general formula (B3): RcOCOCH=C(Ar")2 are reacted in the presence of a nickel compound.
Stereoselective direct copper-catalyzed alkenylation of oxazoles with bromoalkenes
Besselievre, Francois,Piguel, Sandrine,Mahuteau-Betzer, Florence,Grierson, David S.
supporting information; experimental part, p. 4029 - 4032 (2009/06/18)
(Chemical Equation Presented) A copper-catalyzed direct alkenylation of oxazoles with bromoalkenes has been developed. The method is both regio- and stereoselective and tolerates a variety of functional groups. A wide range of 2-E-vinyl-substituted oxazoles were obtained in high yields including the highly fluorescent alkaloid annuloline.