74205-10-0 Usage
Molecular Weight
185.22 g/mol
Physical State
Colorless solid
Usage
Organic synthesis and pharmaceutical research
Role
Important building block in the production of various pharmaceuticals and fine chemicals
Reactivity
High reactivity
Potential
Discovering new drugs
Biological Activities
Studied for anti-inflammatory and anti-cancer properties
Check Digit Verification of cas no
The CAS Registry Mumber 74205-10-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,2,0 and 5 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 74205-10:
(7*7)+(6*4)+(5*2)+(4*0)+(3*5)+(2*1)+(1*0)=100
100 % 10 = 0
So 74205-10-0 is a valid CAS Registry Number.
74205-10-0Relevant articles and documents
Preparation of Indolenines via Nucleophilic Aromatic Substitution
Huber, Florian,Roesslein, Joel,Gademann, Karl
supporting information, p. 2560 - 2564 (2019/03/19)
An unusual aromatic substitution to access indolenines is described. 2-(2-Methoxyphenyl)acetonitrile derivatives are reacted with various alkyl and aryl Li reagents to furnish the corresponding indolenine products, constituents of natural products, and cyanine dyes such as indocyanine green. This new method was used to synthesize 41 indolenines with large functional group tolerance, and selected examples were further converted to the corresponding indolenine dyes. Key experiments provide insight into the mechanism of this nucleophilic aromatic substitution.
