742062-67-5Relevant academic research and scientific papers
A convenient procedure for the synthesis of 3-substituted 5,6-dihydro-4H-1,2-oxazines from nitroethane
Sukhorukov, Alexey Yu.,Klenov, Michael S.,Ivashkin, Pavel E.,Lesiv, Alexey V.,Khomutova, Yulya A.,Ioffe, Sema L.
, p. 97 - 107 (2007/12/31)
A novel and efficient four-step procedure for the synthesis of C-3-functionalised 5,6-dihydro-4H-1,2-oxazines from nitroethane is described. It includes preparation of 3-methyl-substituted six-membered cyclic nitronates, 3-(bromomethyl)-substituted 5,6-dihydro-4H-1,2-oxazines as intermediates, and nucleophilic substitution of bromine. Total yields of the target C-3-functionalised oxazines are 15-30% from nitroethane. Georg Thieme Verlag Stuttgart.
A convenient procedure for the synthesis of substituted 3-α-haloalkyl-5,6-dihydro-4H-1,2-oxazines
Klenov, Michael S.,Lesiv, Alexey V.,Khomutova, Yulya A.,Nesterov, Ivan D.,Ioffe, Sema L.
, p. 1159 - 1170 (2007/10/03)
A general and convenient method for the synthesis of the scarcely known 3-α-haloalkyl-5,6-dihydro-4H-1,2-oxazines 2 via silylation of the corresponding six-membered cyclic nitronates 1 or the first obtained 2-silyloxy-1,2-oxazines 3 by Me3SiX/E
