74260-39-2

Upstream product

• 19350-69-7 4-chlorobenzaldehyde p-toluenesulfonylhydrazone 
• 688-73-3 tri-n-butyl-tin hydride 
• 6655-32-9 N'-(4-chlorobenzylidene)-2-nitrobenzenesulfonohydrazide 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 1461-22-9 tri-n-butylstannyl chloride 
• 20525-51-3 tri(n-butyl)tin cyanide 
• 104-88-1 4-chlorobenzaldehyde 
• 74-11-3 para-chlorobenzoic acid 
• 4217-54-3 9,10-dihydro-10-methylacridine 
• 1461-22-9 tributyltin chloride 
• 2179-92-2 tri-n-butyltin cyanide 
• 74260-35-8 4-(4-Chloro-phenyl)-2,3-dicyano-but-2-enenitrile 

Relevant academic research and scientific papers

Iron Porphyrin Catalyzed Insertion Reaction of N-Tosylhydrazone-Derived Carbenes into X-H (X = Si, Sn, Ge) Bonds

An efficient Fe(TPP)Cl catalyzed insertion reaction of in situ generated benzylic carbenes from N-tosylhydrazones into X-H (X = Si, Sn, Ge) was developed. Silanes bearing tertiary, secondary, and primary (3°, 2°, and 1°) Si-H bonds all reacted well to afford insertion products in moderate to high yields (up to 97%), and the reaction time could be significantly shortened to 1 h under microwave irradiation. A programmable stepwise double insertion strategy was developed for the synthesis of unsymmetrical tetrasubstituted silanes.

Preparation method of alkyl tin compound or benzyl tin compound

The invention discloses a preparation method of an alkyl tin compound or a benzyl tin compound. N-tosylhydrazones, tri-n-butyltin hydride and alkali react in an organic solvent to obtain the alkyl tin compound or the benzyl tin compound. The addition of a phase transfer catalyst can effectively promote the reaction. According to the method disclosed by the invention, it is first time that the alkyl tin compound or the benzyl tin compound is directly obtained under the mild condition from N-tosylhydrazones without transition metal, the reaction efficiency is high, the reaction cost is low, and the method has good tolerance and universality on functional groups and can be widely used for preparing the alkyl tin compound or the benzyl tin compound.

Synthesis of Benzyltributylstannanes by the Reaction of N-Tosylhydrazones with Bu3SnH

An efficient stannylation process with N-tosylhydrazones or directly with carbonyl compounds has been developed. A series of functionalized benzyl- and alkyltributylstannanes can be synthesized in moderate to good yields under transition-metal-free conditions. Tandem transformations involving stannylation/Stille cross-coupling reaction have been carried out without purification of the benzyltributylstannane intermediates to afford a series of diarylmethane derivatives.

Silver(i)-promoted insertion into X-H (X = Si, Sn, and Ge) bonds with N-nosylhydrazones

Silver(i)-promoted carbene insertion into X-H (X = Si, Sn, and Ge) bonds has been realized by using unstable diazo compounds, which are generated in situ from N-nosylhydrazones as carbene precursors. The reaction tolerates a wide range of functional groups and delivers a number of valuable silicon-containing compounds in very high yields (up to 96%). Moreover, organostannanes and organogermanes were as well effectively obtained in very good yields under optimal conditions.