743422-59-5Relevant academic research and scientific papers
Palladium(0)-Catalyzed Intermolecular Asymmetric Cascade Dearomatization Reaction of Indoles with Propargyl Carbonate
Ding, Lu,Gao, Run-Duo,You, Shu-Li
, p. 4330 - 4334 (2019/02/25)
An intermolecular asymmetric cascade dearomatization reaction of indole derivatives with propargyl carbonate was developed. The challenges associated with both the chemoselectivity between the carbon and nitrogen nucleophile and the enantioselective control during the formation of an all-carbon quaternary stereogenic center were well addressed by a Pd catalytic system derived from the Feringa ligand. A series of enantioenriched multiply substituted fused indolenines were provided in good yields (71–86 %) with excellent enantioselectivity (91–96 % ee) and chemoselectivity (3/4>19:1 in most cases).
Intramolecular reactions of 2-indolylacyl radicals: Cyclisation upon aromatic rings
Bennasar, M.-Llu?sa,Roca, Tomàs,Ferrando, Francesc
, p. 5605 - 5609 (2007/10/03)
The generation of 2-indolylacyl radicals from the corresponding selenoesters under reductive (tributyltin hydride-AIBN) and nonreductive (hexabutylditin, 300W) conditions and their behaviour in cyclisation reactions upon benzene rings attached either to t
