74403-57-9

Upstream product

• 3306-69-2 2-aza-bicyclo[2.2.2]octan-3-one 
• 100-39-0 benzyl bromide 
• 3685-23-2 cis-4-aminocyclohexane-1-carboxylic acid 
• 62456-15-9 methyl (1s,4s)-4-aminocyclohexane-1-carboxylate 
• 150-13-0 4-amino-benzoic acid 
• 1776-53-0 4-aminocyclohexanecarboxylic acid 

Downstream Products

• 46410-64-4 2-benzyl-2-aza-bicyclo[2.2.2]octane 
• 87640-24-2 cis-4-<(phenylmethyl)amino>cyclohexanecarboxylic acid 
• 280-38-6 isoquinuclidine 
• 102003-92-9 benzyl-cyclohex-3-enylmethyl-methyl-amine 
• 41959-29-9 2-benzyl-6-trans-hydroxy-2-azabicyclo[2.2.2]octane 
• 10028-34-9 2-benzyl-2-aza-bicyclo[2.2.2]octane-3,6-dione 
• 1160928-99-3 C₁₇H₂₅NOSi 
• 132778-17-7 2-benzyl-2-methyl-2-azonia-bicyclo[2.2.2]octane; iodide 

Relevant academic research and scientific papers

Inhibitors of protein kinases

Compounds of general Formula (I): wherein R1, R2, R3, Ra, A, B and x are as defined herein are inhibitors of protein kinases in particular members of the cyclin-dependent kinase family and/or the glycogen synthase kinase 3 family and are useful in preventing and/or treating any type of pain, inflammatory disorders, cancer, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases, metabolic disorders, renal diseases, neurologic and neuropsychiatric diseases and neurodegenerative diseases.

TRANSFORMATIONS MICROBIOLOGIQUES-3 APPROCHE DE LA TOPOLOGIE DU SITE HYDROXYLANT DE BEAUVERIA SULFURESCENS

Hydroxylation of some bi- or tricyclic amides or lactams, the determination of the absolute configuration of the alcohols obtained and the topology of the hydroxylating site of Beauveria sulfurescens based on these absolute configurations, are discussed.