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4-Pyrimidinecarboxylic acid, 6-chloro-2-methyl-, ethyl ester, with the CAS Number 85391-59-7, is a chemical compound that falls under the pyrimidines category. It features a pyrimidine ring with chlorine and methyl groups as substituents, and its carboxylic acid functional group is esterified with an ethyl group. Pyrimidines are significant in various biological applications, including DNA and RNA synthesis. Comprehensive details about its safety, potential hazards, and reactivity with other substances can be found in its Material Safety Data Sheet (MSDS).

744253-37-0

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744253-37-0 Usage

Uses

Used in Pharmaceutical Industry:
4-Pyrimidinecarboxylic acid, 6-chloro-2-methyl-, ethyl ester is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique structure with a pyrimidine ring and substituents allows it to be a key component in the development of new drugs, particularly those targeting DNA and RNA synthesis pathways.
Used in Chemical Research:
In the field of chemical research, 4-Pyrimidinecarboxylic acid, 6-chloro-2-methyl-, ethyl ester serves as a valuable compound for studying the properties and reactions of pyrimidines. Its reactivity with other substances can provide insights into the development of new chemical processes and the synthesis of novel compounds.
Used in Material Science:
4-Pyrimidinecarboxylic acid, 6-chloro-2-methyl-, ethyl ester is used as a building block in the synthesis of advanced materials, such as polymers and composites. Its incorporation into these materials can impart unique properties, such as improved stability or enhanced reactivity, which can be beneficial in various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 744253-37-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,4,2,5 and 3 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 744253-37:
(8*7)+(7*4)+(6*4)+(5*2)+(4*5)+(3*3)+(2*3)+(1*7)=160
160 % 10 = 0
So 744253-37-0 is a valid CAS Registry Number.

744253-37-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl 6-chloro-2-methylpyrimidine-4-carboxylate

1.2 Other means of identification

Product number -
Other names ethyl 6-chloro-2-methylpyrimidine-4-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:744253-37-0 SDS

744253-37-0Downstream Products

744253-37-0Relevant academic research and scientific papers

Synthesis of benzoylpyrimidines as antagonists of the corticotropin- releasing factor-1 receptor

Webb, Thomas R.,Moran, Terry,Huang, Charles Q.,McCarthy, James R.,Grigoriadis, Dimitri E.,Chen, Chen

, p. 3869 - 3873 (2004)

A series of benzoylpyrimidines derived from the anilinepyrimidine CRF 1 antagonists were synthesized. Several synthetic routes were developed to explore the SAR of this series of compounds. Compounds such as 8d (Ki=15nM) exhibited high binding affinities at the human CRF 1 receptor.

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