10302-94-0 Usage
General Description
Alpha-Chlorofumaric Acid Diethyl Ester is a chemical compound with the molecular formula C8H11ClO4. It is an ester derivative of alpha-chlorofumaric acid, which is commonly used in organic synthesis and pharmaceutical research. ALPHA-CHLOROFUMARICACIDDIETHYLESTER is known for its ability to undergo various chemical reactions, such as esterification, hydration, and hydrolysis, making it a versatile building block for the synthesis of other organic compounds. It is also used as a reagent in the production of pharmaceuticals, agrochemicals, and other fine chemicals. This chemical is a colorless liquid with a slightly fruity odor, and it is considered to be moderately hazardous if ingested, inhaled, or in contact with skin and eyes.
Check Digit Verification of cas no
The CAS Registry Mumber 10302-94-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,0 and 2 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 10302-94:
(7*1)+(6*0)+(5*3)+(4*0)+(3*2)+(2*9)+(1*4)=50
50 % 10 = 0
So 10302-94-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H11ClO4/c1-3-12-7(10)5-6(9)8(11)13-4-2/h5H,3-4H2,1-2H3/b6-5-
10302-94-0Relevant articles and documents
Woodward,Reed
, p. 1569,1570 (1943)
Synthesis of benzoylpyrimidines as antagonists of the corticotropin- releasing factor-1 receptor
Webb, Thomas R.,Moran, Terry,Huang, Charles Q.,McCarthy, James R.,Grigoriadis, Dimitri E.,Chen, Chen
, p. 3869 - 3873 (2007/10/03)
A series of benzoylpyrimidines derived from the anilinepyrimidine CRF 1 antagonists were synthesized. Several synthetic routes were developed to explore the SAR of this series of compounds. Compounds such as 8d (Ki=15nM) exhibited high binding affinities at the human CRF 1 receptor.
