7449-27-6

Usage

InChI:InChI=1/C8H8N4O6/c1-2-9-8-6(11(15)16)3-5(10(13)14)4-7(8)12(17)18/h3-4,9H,2H2,1H3

Upstream product

• 6052-13-7 N-nitro-N-ethyl-2,4,6-trinitroaniline 
• 5429-28-7 4-(diethylamino)benzoic acid 
• 7697-37-2 nitric acid 
• 10287-54-4 p-N,N-diethylaminobenzoic acid ethyl ester 
• 67263-27-8 2,4,6-trinitro-1-piperidinobenzene 
• 13029-07-7 1-diethylamino-2,4,6-trinitro-benzene 
• 2493-31-4 N,N-dimethyl-2,4,6-trinitro-aniline 
• 88-88-0 2,4,6-trinitrochlorobenzene 
• 131170-45-1 1-(N-Methyl)butylamino-2,4,6-trinitrobenzene 
• 75-04-7 ethylamine 
• 77379-02-3 2,4,6-trinitro-1-pyrrolidinobenzene 
• 14677-67-9 phenyl-picryl sulfone 
• 64-17-5 ethanol 

Downstream Products

• 20722-57-0 N-ethyl-2',4',6'-trinitroacetanilide 

Relevant academic research and scientific papers

Cyclisation of N-alkyl-2,4-dinitro-6-trifluoromethylanilines

Examples of cyclisation of the title compounds leading to 2-alkyl substituted benzimidazole N-oxides are reported.

Aromatic nucleophilic substitution reactions of 1-dialkylamino-substituted activated benzenes with various amines in dimethyl sulfoxide

In the reactions of 1-dlalkylamino-2,4,6-trinitro- and 1-dialkylamlno-2, 4-dinitrobenzenes with various amines in dimethyl sulfoxide, 1-dialkylamino group is easily replaced with primary n-alkylamines at room temperature, and in a low yield with pyrrolidine only among secondary amines.

Kinetics of the Reactions of Nitro-substituted N-Alkylacetanilides with Sodium Methoxide in Methanol

The sodium methoxide-catalysed methanolysis of N-ethyl (3) or N-methyl-2',4',6'-trinitroacetanilide (4) is found to proceed with initial formation of a 1,3-disubstituted anionic ?-complex (II), which then reverts to the reactant system, relatively slowly giving N-alkyl-4-methoxy-(main product) and N-alkyl-2'-methoxy-4',6'-dinitroacetanilides with the amido group unchanged, via a 1,4-disubstituted anionic ?-complex (III); kinetics and absorption and 1H n.m.r. spectral data are reported.