5429-28-7

Basic information

• Product Name: 4-DIETHYLAMINOBENZOIC ACID
• Synonyms: LABOTEST-BB LT00848191;4-DIETHYLAMINOBENZOIC ACID;4-(N,N-DIETHYLAMINO)BENZOIC ACID;AKOS BBS-00003738;RARECHEM AL BO 2370;P-(N,N-DIETHYLAMINO) BENZOIC ACID;4-(diethylamino)-benzoicaci;Benzoic acid, 4-(diethylamino)-
• CAS NO: 5429-28-7
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.24
• EINECS: 226-582-8
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Aromatic Amino Acids;Peptide Synthesis;Unnatural Amino Acid Derivatives
• Mol File: 5429-28-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 192-193 °C(lit.)
• Boiling Point: 329.46°C (rough estimate)
• Flash Point: 175°C
• Appearance: Light green/Fine Crystalline Powder
• Density: 1.117
• Vapor Pressure: 3.25E-05mmHg at 25°C
• Refractive Index: 1.5041 (estimate)
• Storage Temp.: Store below +30°C.
• Solubility: Soluble in hot methanol.
• PKA: 3.65±0.10(Predicted)
• BRN: 2211601
• CAS DataBase Reference: 4-DIETHYLAMINOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-DIETHYLAMINOBENZOIC ACID(5429-28-7)
• EPA Substance Registry System: 4-DIETHYLAMINOBENZOIC ACID(5429-28-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 5429-28-7(Hazardous Substances Data)

Usage

Uses

4-(Diethylamino)benzoic acid is used as a reactant in the preparation of amides by acylation of amines using (acyl)benzotriazoles.

InChI:InChI=1/C11H15NO2/c1-3-12(4-2)10-7-5-9(6-8-10)11(13)14/h5-8H,3-4H2,1-2H3,(H,13,14)/p-1

Upstream product

• 74974-49-5 (4-(diethylamino)phenyl)methanol 
• 150-13-0 4-amino-benzoic acid 
• 75-03-6 ethyl iodide 
• 103-69-5 N-ethyl-N-phenylamine 
• 91-66-7 N,N-diethylaniline 
• 120-21-8 4-Diethylaminobenzaldehyde 
• 75-44-5 phosgene 
• 64-17-5 ethanol 
• 655-32-3 2,2,2-trifluoro-1-(4-fluorophenyl)ethanone 
• 65613-24-3 p-Diethylamino-α,α,α-trifluoracetophenon 
• 7782-99-2 sulphurous acid 
• 124-38-9 carbon dioxide 
• 2052-06-4 4-bromo-N,N-diethylaniline 

Downstream Products

• 10287-54-4 p-N,N-diethylaminobenzoic acid ethyl ester 
• 65419-31-0 4-[5-(4-chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-N,N-diethyl-aniline 
• 91563-80-3 4-diethylamino-benzoic acid methyl ester 
• 65072-47-1 4-diethylaminobenzoyl chloride 
• 945-81-3 N-nitroso N-ethyl-N-(4-nitroaniline) 
• 2216-15-1 1-diethylamino-4-nitrobenzene 
• 3846-50-2 2,4-dinitro-N-ethylaniline 
• 837-64-9 N,N-diethyl-2,4-dinitroaniline 
• 2788-74-1 4-(ethylamino)-3-nitrobenzoic acid 
• 7449-27-6 N-ethyl-2,4,6-trinitroaniline 
• 861782-56-1 4-(diethyl-oxy-amino)-benzoic acid 
• 369358-85-0 N'-((2RS,3R)-3-amino-5-(ethylsulfanyl)-2-hydroxypentanoyl)-4-(diethylamino)benzohydrazide 

Relevant articles and documents

A Cross-linked Conjugated Polymer Photosensitizer Enables Efficient Sunlight-Induced Photooxidation

Photooxidation under sunlight has potential in organic synthesis, bacterial killing, and organic waste treatment. Photosensitizers (PSs) can play an important role in this process. High 1O2 generation efficiency and excellent photostability under sunlight, as well as easy recyclability are ideal properties for PSs, but are not easy to achieve simultaneously. Herein, a pure organic porous conjugated polymer PS, CPTF, shows great photostability, large specific surface area, and high 1O2 generation efficiency under sunlight for photooxidation. For the oxidation of aromatic aldehyde to aromatic acid, the PS catalyst shows excellent recyclability, and enables solvent-free reactions in high yields both under direct sunlight and simulated AM 1.5G irradiation. In addition, the successful application of CPTF as an antibacterial agent and organic waste decomposition under simulated AM 1.5G irradiation indicates the potential of CPTF in sunlight-induced waste water treatment.

A practical method for the preparation of 4-nitrogen-substituted benzoic acids

An efficient and practical method for the preparation of 4-nitrogen-substituted benzoic acids is described. Our method consists of the aromatic substitution of 2,2,2,4′-tetrafluoroacetophenone with amines, followed by haloform reaction to the benzoic acids. In this method, even though for the less nucleophilic 7-, 8-, and 9-membered amines 1 equiv. was used, corresponding benzoic acids were obtained in moderate to excellent yield. As the experimental procedure including purification is simple, this method is applicable to large-scale syntheses. Copyright