74611-50-0 Usage
Uses
Used in Organic Synthesis:
3-CYANO-2-(N-BUTYLAMINO)PYRIDINE is used as a building block for the synthesis of various organic compounds due to its versatile chemical reactivity and structural features.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3-CYANO-2-(N-BUTYLAMINO)PYRIDINE is utilized as a key intermediate in the development of new drugs. Its unique structure contributes to the design of molecules with potential therapeutic properties.
Used in Agrochemical Development:
3-CYANO-2-(N-BUTYLAMINO)PYRIDINE also finds application in the agrochemical sector, where it serves as a precursor in the synthesis of compounds with pesticidal or herbicidal activities, leveraging its chemical properties to create effective crop protection agents.
Used in Medicinal Chemistry:
Researchers in medicinal chemistry explore the biological activities of 3-CYANO-2-(N-BUTYLAMINO)PYRIDINE, aiming to understand and harness its potential for the creation of novel therapeutic agents.
Used in Pharmacology:
Pharmacologists are interested in 3-CYANO-2-(N-BUTYLAMINO)PYRIDINE because of its demonstrated biological activities, which may lead to the discovery of new drugs with specific pharmacological effects.
Check Digit Verification of cas no
The CAS Registry Mumber 74611-50-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,6,1 and 1 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 74611-50:
(7*7)+(6*4)+(5*6)+(4*1)+(3*1)+(2*5)+(1*0)=120
120 % 10 = 0
So 74611-50-0 is a valid CAS Registry Number.
74611-50-0Relevant academic research and scientific papers
2-(Alkylamino)nicotinic Acid and Analogs. Potent Angiotensin II Antagonists
Winn, Martin,De, Biswanath,Zydowsky, Thomas M.,Altenbach, Robert J.,Basha, Fatima Z.,et al.
, p. 2676 - 2688 (2007/10/02)
A series of pyridines and other six-membered ring heterocycles connected to a biphenyltetrazole with a-CH2-NR'-link (1) were discovered to be potent angiotensin II antagonists.In the pyrimidine carboxylic acid series (W = CR, X = N, Y = CH, Z = COOH), compounds with an alkyl group (R') on the exocyclic nitrogen were much more potent than compounds with an alkyl group (R) on the heterocyclic ring.The corresponding pyridine, pyridazine, pyrazine, and 1,2,4-triazine carboxylic acids also showed potent in vitro angiotensin II antagonism.The pyridine (W, X, Y = CH, Z = COOH, R' = n-C3H7) demonstrated potent in vitro activity (pA2 = 10.10, rabbit aorta, and Ki = 0.61 nM, receptor binding in rat liver) as well as exceptional oral antihypertensive activity and bioavailability.Any nonacidic replacement for the carboxylic acid was detrimental for activity.
Angiotensin II receptor antagonists
-
, (2008/06/13)
Compounds are disclosed having the formula: STR1 The compounds of the invention are angiotensin II receptor antagonists.
