74611-53-3 Usage
Uses
Used in Pharmaceutical Industry:
2-(Butylamino)nicotinic acid is used as a potential therapeutic agent for various conditions due to its potential biological activities. It is being researched for its ability to act as a vasodilator, which could help in the treatment of cardiovascular diseases by improving blood flow. Additionally, its anti-inflammatory properties make it a candidate for the treatment of inflammatory conditions.
Used in Cardiovascular Applications:
In the field of cardiovascular medicine, 2-(Butylamino)nicotinic acid is used as a potential vasodilator for the treatment of cardiovascular diseases. Its vasodilatory effects could help in reducing the symptoms and complications associated with these conditions by improving blood flow and reducing the workload on the heart.
Used in Metabolic Disorders:
2-(Butylamino)nicotinic acid is used as a potential treatment for metabolic disorders due to its potential role in regulating metabolic processes. It may help in managing conditions such as diabetes or obesity by improving the body's ability to process and utilize nutrients.
Used in Cancer Treatment:
2-(Butylamino)nicotinic acid is used as a potential anticancer agent in the field of oncology. It is being studied for its potential to inhibit the growth and spread of cancer cells, making it a candidate for the development of new cancer therapies. Further research is needed to fully understand its effects and potential applications in cancer treatment.
Used in Research and Development:
2-(Butylamino)nicotinic acid is used as a subject of study in pharmaceutical research and development. Its potential biological activities and applications in various medical fields make it an important compound for further investigation, with the aim of developing new drugs and therapies based on its properties.
Check Digit Verification of cas no
The CAS Registry Mumber 74611-53-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,6,1 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 74611-53:
(7*7)+(6*4)+(5*6)+(4*1)+(3*1)+(2*5)+(1*3)=123
123 % 10 = 3
So 74611-53-3 is a valid CAS Registry Number.
74611-53-3Relevant academic research and scientific papers
Synthesis of 2-(arylamino)nicotinic acids in high-temperature water
Li, Zhenghua,Xiao, Shangyou,Liang, Ronghui,Xia, Zhining
, p. 1691 - 1697 (2012/10/29)
In hydrothermal reactions at 150-180 °C, 2-(arylamino)nicotinic acids were synthesized by amination of 2-chloronicotinic acid with aromatic amine derivatives, with potassium carbonate as base. The procedure is efficient, environmentally friendly, and practical, with moderate to excellent yields (up to 98%). Springer Science+Business Media B.V. 2012.
Microwave-assisted synthesis of 2-aminonicotinic acids by reacting 2-chloronicotinic acid with amines
Quevedo, Camilo E.,Bavetsias, Vassilios,McDonald, Edward
experimental part, p. 2481 - 2483 (2009/08/17)
2-(Methylamino)nicotinic acid was readily prepared in high yield by reacting 2-chloronicotinic acid with 40% aq MeNH2 under microwave irradiation either at 120 °C for 2 h or at 140 °C for 1.5 h. Subsequently, we found that a range of 2-aminonicotinic acids could be obtained under microwave heating. The optimal reaction conditions involved the use of 3 equiv of amine, water as the solvent and heating at 200 °C for 2 h in the presence of diisopropylethylamine (3 equiv).
Synthesis of SMP-797: A new potent ACAT inhibitor
Ban, Hitoshi,Muraoka, Masami,Ohashi, Naohito
, p. 10081 - 10092 (2007/10/03)
A potent ACAT (acyl-CoA: cholesterol acyltransferase) inhibitor SMP-797 was effectively synthesized by the urea formation of 3-amino-4-aryl-1,8- naphthyridin-2(1H)-one and 4-amino-2,6-diisopropylamine. The synthesis of the former compound involved the Suzuki coupling reaction as a key step, and the latter was prepared by the 4-selective nitration of 2,6-diisopropylaniline using 2,3,5,6-tetrabromo-4-methyl-4-nitro-2,5-cyclohexadienone.
A convenient synthesis of 4-aryl-1,8-naphthyridin-2(1H)-ones by the Suzuki coupling
Ban, Hitoshi,Muraoka, Masami,Ohashi, Naohito
, p. 6021 - 6023 (2007/10/03)
4-Halo-1,8-naphthyridin-2(1H)-ones readily available from 2-chloronicotinic acid were subjected to the Suzuki coupling reaction with arylboronic acids to give a diversity of 4-aryl-1,8-naphthyridin-2(1H)-ones.
