7464-17-7

Usage

Uses

Used in Antimicrobial Applications:
1-(4-chlorophenyl)-3-(diaminomethylidene)thiourea is used as an antimicrobial agent for its potential to treat various bacterial and fungal infections. Its chlorophenyl and diaminoalkylidene groups contribute to its effectiveness against a range of pathogens.
Used in Antifungal Applications:
In the medical industry, 1-(4-chlorophenyl)-3-(diaminomethylidene)thiourea is used as an antifungal agent, particularly effective against dermatophytes, which are fungi responsible for skin infections.
Used in Acne Treatment:
1-(4-chlorophenyl)-3-(diaminomethylidene)thiourea is also being investigated for its potential use in the treatment of acne due to its antimicrobial properties, which can help combat the bacteria that contribute to the development of acne.
Further research is necessary to fully understand the therapeutic uses and safety profile of 1-(4-chlorophenyl)-3-(diaminomethylidene)thiourea, but its potential applications in various industries make it a compound of interest for future pharmaceutical development.

Upstream product

• 50-01-1 guanidine hydrochloride 
• 2131-55-7 4-Chlorophenyl isothiocyanate 
• 196877-91-5 1-(4-Chloro-phenyl)-3-[(3,5-dimethyl-pyrazol-1-yl)-imino-methyl]-thiourea 
• 113-00-8 guanidine nitrate 
• 124-46-9 guanidine hydrogen carbonate 
• 593-84-0 guanidinium thiocyanate 

Downstream Products

• 1154520-35-0 3-(4-acetyl-phenyl)-2-[4-amino-2-(4-chlorophenylamino)-thiazol-5-yl]-3H-quinazolin-4-one 
• 1154520-34-9 2-[4-amino-2-(4-chloro-phenylamino)-thiazol-5-yl]-3-(4-chloro-phenyl)-3H-quinazolin-4-one 
• 857010-29-8 1-(4-chloro-phenyl)-6,6,N²-trimethyl-1,6-dihydro-[1,3,5]triazine-2,4-diyldiamine 
• 107401-72-9 [4-amino-2-(4-chlorophenylamino)thiazol-5-yl](4-chlorophenyl)methanone 
• 132533-34-7 N⁵-(4-Chloro-phenyl)-[1,2,4]thiadiazole-3,5-diamine 
• 857396-97-5 N-carbamimidoyl-N'-(4-chloro-phenyl)-S-methyl-isothiourea 
• 46440-97-5 1-(4-chloro-phenyl)-2-methyl-biguanide 

Relevant academic research and scientific papers

NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS

The present invention disclosed a novel EGFR inhibitor compound of formula (I), process for preparation thereof and methods of treating abnormal cell growth in mammals by administering the compounds of formula (I). Wherein, R= -H, 3-CH3, 4-NO2, 4-Cl, 2-CH3, 4-CH3, 4-Br, 4-F R1= -H, -4-OCH3, -4-NO2,-2-NO2, -4-Cl, -2,4,6-CH3, -4-CH3, -2-F,4-Br, -4-CF3, -4-S-CH3, -4-Cl,-3-CF3, -3-S-CH3, -3,5-CF3, -2-S-CH3, -3-CF3,-4-OCF3, -Si-(CH3)3, -Si-(C2H5)3, (CH3)2-Si- C2H5.

Design, synthesis and characterization of novel 2-(2,4-disubstituted-thiazole-5-yl)-3-aryl-3H-quinazoline-4-one derivatives as inhibitors of NF-κB and AP-1 mediated transcription activation and as potential anti-inflammatory agents

A series of 2-(2,4-disubstituted-thiazole-5-yl)-3-aryl-3H-quinazoline-4-one derivatives were designed and synthesized. Synthesized molecules were further evaluated for their inhibitory activity towards transcription factors NF-κB and AP-1 mediated transcr

Studies in the antimicrobial activities of 1-substituted-3-formamidinothio- carbamides and 1,3-bis-(substitutedthioamido)guanidines

The present research work has been undertaken in the synthesis of nitrogen, nitrogen and sulphur containing heteroacycles and heterocycles and to investigate their applications in medicinal, agricultural, industrial, pharmacological and biochemical facult

Conversion of alkylamines to thiocarbamoylguanidines

N-Alkyl-, N,N-dialkyl- or N-unsubstituted-N'-(arylthiocarbamoyl)guanidines are prepared in very good yield from amines and 1-(N-arylthiocarbamoyl)amidino3,5 -dimethylpyrazoles.