7473-90-7

Usage

InChI:InChI=1/C11H13NO2/c1-2-6-10(13)12-11(14)9-7-4-3-5-8-9/h3-5,7-8H,2,6H2,1H3,(H,12,13,14)

Upstream product

• 106-31-0 butanoic acid anhydride 
• 55-21-0 benzamide 
• 141-75-3 butyryl chloride 
• 97485-16-0 4-Phenyl-2-propyl-4H-oxazol-5-one 
• 51767-61-4 (E,Z)-2-phenyl-4-propylidene-4,5-dihydrooxazol-5-one 
• 82734-96-1 butyryl-α-phenylglycine 
• 98-88-4 benzoyl chloride 
• 163685-98-1 N-phenylbutyrimidamide 
• 134-81-6 benzil 
• 100-47-0 benzonitrile 
• 541-35-5 butanamide 
• 100-52-7 benzaldehyde 
• 2432-51-1 ethylthioacetic acid methyl ester 
• 825-60-5 benzimidic acid ethyl ester 

Relevant academic research and scientific papers

Visible-Light-Driven Oxidation of N -Alkylamides to Imides Using Oxone/H 2 O and Catalytic KBr

Imides are prepared conveniently by visible-light-driven oxidations of various N -alkylamides under mild conditions. The majority of the reactions proceed efficiently by using Oxone as the oxidant in the presence of a catalytic amount of KBr in H 2 O/CH 2 Cl 2 under irradiation by an 8 W white LED at room temperature. Experimental studies suggest that an imine, obtained from the substrate amide via a radical process, is the key intermediate.

Vanadium-Catalyzed Oxidative C(CO)-C(CO) Bond Cleavage for C-N Bond Formation: One-Pot Domino Transformation of 1,2-Diketones and Amidines into Imides and Amides

A novel vanadium-catalyzed one-pot domino reaction of 1,2-diketones with amidines has been identified that enables their transformation into imides and amides. The reaction proceeds by dual acylation of amidines via oxidative C(CO)-C(CO) bond cleavage of 1,2-diketones to afford N,N′-diaroyl-N-arylbenzamidine intermediates. In the reaction, these intermediates are easily hydrolyzed into imides and amides through vanadium catalysis. This method provides a practical, simple, and mild synthetic approach to access a variety of imides as well as amides in high yields. Moreover, one-step construction of imide and amide bonds with a long-chain alkyl group is an attractive feature of this protocol.

N-Butylammonium carboxylates/Tf2O: Ionic liquid based systems for the synthesis of unsymmetrical imides via a Ritter-type reaction

We have developed a new method for the preparation of unsymmetrical imides using liquid carboxylate salts via a Ritter-type process. The reactions were carried out with nitriles and n-butylammonium carboxylates as ionic liquids in the presence of triflic anhydride (Tf2O) as the promoter. Mild reaction conditions, simplicity of the procedure, and proton-free conditions are the main advantages of this procedure.

Highly efficient iron(II) chloride/N-bromosuccinimide-mediated synthesis of imides and acylsulfonamides

We have developed a general and highly efficient iron(II) chloride/N-bromosuccinimide (NBS)-mediated method for the synthesis of imides and acylsulfonamides via couplings of thioesters with carboxamides/sulfonamides, and the method is simple, economical and shows practical advantages.

Highly efficient copper-catalyzed amidation of aldehydes by C-H activation

We have developed a highly efficient method for the copper-catalyzed amidation of aldehydes in the presence of N-bromosuccinimide (NBS). This method is simple, economical, and has practical advantages for synthesis of imides.

Synthesis of imides, N-acyl vinylogous carbamates and ureas, and nitriles by oxidation of amides and amines with dess-martin periodinane

Expanding our synthetic tool repertoire: The DMP-mediated oxidation of a range of amide substrates has been demonstrated, affording the corresponding imides and N-acyl vinylogous carbamates and ureas. Likewise, an array of benzylic and related amines have also been successfully converted into their nitrile counterparts (see scheme; DMP = Dess-Martin periodinane). (Chemical Equation Presented)

Photodecarbonylation of 2-phenyl-4-alkylidene-5(4H)-oxazolones

The title compounds were prepared by the Erlenmeyer synthesis and irradiated with or without a Pyrex filter using 450 W medium pressure mercury arc lamp. Cis-trans isomerization was the major reaction under pyrex filtered condition, whereas irradiation without a Pyrex filter resulted in decarbonylation, followed by trapping of the ketenimine intermediate by protic solvents.

Hydrogen bond directed cocrystallization and molecular recognition properties of acyclic imides

The cocrystalization behavior of acyclic is studied as a way to map out the hydrogen bond directed molecular recognition properties of a class of small biochemically molecules under where is no preorganized cavity controlling the recognition events. Cocry

AN EFFICIENT TRANSFORMATION OF N-ACYL-α-AMINO ACIDS INTO DIACYLAMINES VIA 2,4-DISUBSTITUTED OXAZOL-5(4H)-ONES

Base-catalyzed oxygenative decarboxylation of a variety of 2,4-disubstituted oxazol-5(4H)-ones in benzene with triethylamine or in dimethylsulfoxide with potassium tert-butoxide gives diacylamines.KEYWORDS - base-catalyzed autooxidation; selective oxygenation; decarboxylation; oxazol-5(4H)-one; N-acyl-α-amino acid; diacylamine