74738-17-3

Usage

Metabolic pathway

Limited data are available in the open literature. Information presented in this summary was abstracted from the data evaluation published by the Pesticide Safety Directorate (PSD, 1993). Fenpiclonil is stable to hydrolytic and soil degradation. Photolytic degradation is rapid. Hydroxylation and oxidation of the pyrrole ring are the primary metabolic reactions in plants and animals (Scheme 1).

Degradation

Fenpiclonil (1) is stable to hydrolytic degradation (up to 70 °C) over the pH range 5-9. Fenpiclonil degraded rapidly in water (pH 7) when samples were irradiated under a mercury arc lamp (>290 nm) with an estimated DT50 values of <1 hour. At least eight unidentified degradation products were observed

InChI:InChI=1/C11H6Cl2N2/c12-10-3-1-2-8(11(10)13)9-6-15-5-7(9)4-14/h1-3,5-6,15H

Upstream product

• 35520-41-3 trans-3-dimethylaminoacrylonitrile 
• 125072-41-5 2',3'-dichloro-cinnamic nitril 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 139276-29-2 (E)-2-(2,3-Dichlorophenyl)-1-isocyano-tosylethene 
• 105-56-6 ethyl 2-cyanoacetate 
• 139276-33-8 (E)-N-<2-(2,3-Dichlorophenyl)-1-tosylethenyl>formamide 
• 6334-18-5 2,3-dichlorobenzylaldehyde 

Downstream Products

• 74738-11-7 1-acetyl-3-cyano-4-(2,3-dichlorophenyl) pyrrole 
• 156428-56-7 4-(2,3-dichlorophenyl)-1-methylpyrrole-3-carbonitrile 

Relevant academic research and scientific papers

Phenyl pyrrole compound and application thereof in bactericidal activity

The invention provides a novel phenyl pyrrole compound, and the phenyl pyrrole compound shows good bactericidal activity and can be used for preparing a broad-spectrum plant bactericide. In addition,the synthesis route is simple, the operation is convenient, the synthesis cost is reduced, and ecological environment pollution to soil, surface water, underground water and the like is avoided.

Nitrogen-substituted phenyl pyrrole compound and application thereof in plant sterilization

The invention provides a novel nitrogen-substituted phenyl pyrrole compound. The phenyl pyrrole compound shows good bactericidal activity and can be used for preparing bactericides with high-selectivity sterilization. Moreover, the synthesis route is simple, the operation is convenient, the synthesis cost is reduced, and ecological environment pollution to soil, surface water, underground water and the like is avoided.

Synthesis of 3,4-Disubstituted Pyrroles Bearing Substituents of Electron-Withdrawing and/or Electron-Donating Nature

The synthesis is described of a series of 3,4-disubstituted pyrroles 8 from 1-isocyano-1-tosyl-1-alkenes and a variety of Michael donors.It is possible to use this method for the synthesis of pyrroles that bear no electron-withdrawing substituents.

Process for the preparation of 3-phenylpyrrole derivatives

3-Phenylpyrrole derivatives of formula I STR1 wherein X is cyano, --CO--R3, --CO--OR3 or STR2 R1 and R2 are each independently of the other hydrogen, C1 -C6 alkyl, C1 -C6/s

Process for the preparation of 3-cyano-4-aryl-pyrroles

A process for the preparation of a 3-cyano-4-aryl-pyrrole of the formula STR1 in which Ar is optionally substituted heteroaryl or aryl, which comprises (a) reacting an α-cyanoacrylic acid derivative of the formula STR2 in which R1 is amino or alkoxy, with an isocyanoacetic acid ester of the formula STR3 in which R2 is alkyl, in the presence of a base thereby to produce a Δ2 -pyrroline-2-carboxylic acid derivative of the formula STR4 in which X represents hydrogen or an equivalent of an inorganic or organic cation, and (b) oxidatively decarboxylating the Δ2 -pyrroline-2-carboxylic acid. The end products are known fungicides and the intermediates IVa are new and themselves fungicidally active.

Process for the production of 3-phenyl-4-cyanopyrroles

A process for the production of a compound having the formula: STR1 which comprises a reaction of a compound having the formula: STR2 with a compound having the formula wherein X is same or different substituent(s) selected from the group consisting of ha

Process for the preparation of 4-phenylpyrrole derivatives

The invention relates to a process for the preparation of 4-phenylpyrrole derivatives of the formula I STR1 wherein Rn, R1 and R2 are as defined in claim 1, which comprises reacting a phenacylamine of formula II STR2 with

Production for producing 3-cyano-4-phenyl indoles and intermediates

There is described a process for producing fungicidally active 4-phenylpyrrole derivatives of the formula I STR1 wherein R is halogen, C1 -C6 -alkyl or C1 -C6 -haloalkyl, and n is 0, 1 or 2, which process compri

Cyanopyrrole derivatives

Compounds of the general formula STR1 wherein X is halogen, lower alkyl or lower haloalkyl, and n is 0, 1 or 2; are outstanding effective fungicides.