7474-92-2

Basic information

• Product Name: dimethyl 3,6-dihydroxybenzene-1,2-dicarboxylate
• CAS NO: 7474-92-2
• Molecular Formula: C₁₀H₁₀O₆
• Molecular Weight: 226.1828
• Mol File: 7474-92-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 346.2°C at 760 mmHg
• Flash Point: 134.9°C
• Density: 1.395g/cm³
• Vapor Pressure: 2.93E-05mmHg at 25°C
• Refractive Index: 1.575
• CAS DataBase Reference: dimethyl 3,6-dihydroxybenzene-1,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 3,6-dihydroxybenzene-1,2-dicarboxylate(7474-92-2)
• EPA Substance Registry System: dimethyl 3,6-dihydroxybenzene-1,2-dicarboxylate(7474-92-2)

Safety Data

• Hazardous Substances Data: 7474-92-2(Hazardous Substances Data)

Usage

General Description

Dimethyl 3,6-dihydroxybenzene-1,2-dicarboxylate is a chemical compound with a molecular formula C12H12O8. It is commonly known as caffeic acid dimethyl ester and is derived from caffeic acid, a naturally occurring organic compound found in various plants. dimethyl 3,6-dihydroxybenzene-1,2-dicarboxylate is known for its antioxidant and potential anti-inflammatory properties, making it a topic of interest in the field of medicine and pharmaceuticals. It has shown promise in the treatment of various diseases and conditions, including neurodegenerative disorders and cancer. Additionally, it has also been studied for its potential use in skincare and cosmetic products due to its antioxidant and anti-aging properties.

Upstream product

• 67-56-1 methanol 
• 3786-46-7 3,6-dihydroxyphthalic acid 
• 86528-19-0 dimethyl 3,6-di-tert-butoxyphthalate 
• 77220-06-5 2,5-bis<(trimethylsilyl)oxy>furan 
• 624-48-6 dimethyl cis-but-2-ene-1,4-dioate 
• 59733-55-0 1,4-bis((trimethylsilyl)oxy)cyclohexa-1,3-diene 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 74590-73-1 1,3-bis(trimethylsiloxy)-1-methoxybuta-1,3-diene 
• 4733-50-0 2,3-dicyano-1,4-hydroquinone 
• 106-51-4 p-benzoquinone 

Downstream Products

• 103548-64-7 dimethyl 3,4,6-trihydroxyphthalate 
• 105518-06-7 dimethyl 3,4,6-triacetoxyphthalate 
• 1459157-11-9 2-(1-hydroxyheptyl)-3-(hydroxymethyl)benzene-1,4-diol 
• 1459157-14-2 (E)-2-(hept-1-en-1-yl)-3-(hydroxymethyl)benzene-1,4-diol 
• 14597-12-7 3,6-dimethoxyphthalic anhydride 
• 220398-58-3 3,6-bis-dimethylcarbamoylsulfanyl-phthalic acid dimethyl ester 
• 220398-59-4 (2-hydroxymethyl-3,6-dimercapto-phenyl)-methanol 

Relevant articles and documents

Total Synthesis of Violaceoid A and (-)- and (+)-Violaceoid B

The first total synthesis of violaceoid A, a cytotoxic agent, and the asymmetric total synthesis of (-)- and (+)-violaceoid B are reported. The precursor was accessed by desymmetrization of a substituted quinol moiety, and the racemic secondary alcohol wa

CYCLOADDITION OF 1,4-BIS-TRIMETHYLSILOXY-1,3-CYCLOHEXADIENE

The cycloaddition reactions of 1,4-bis-trimethylsiloxy-1,3-cyclohexadiene with maleic anhydride, dimethyl acetylenedicarboxylate, diethyl fumarate and methyl acrylate have been studied.The moderate to good yields obtained in these reactions indicate that this diene will be useful in the synthesis of 1,4-oxygenated bicyclooctanes.

Diels-Alder Syntheses with 1,4-Di-tert-butoxy-1,3-butadiene

The title compound (DTBU) enters into cycloadditions with fumaronitrile, tetracyanoethene, maleic anhydride, diethyl azodicarboxylate, 1,2-dibenzoylethene, dimethyl acetylenedicarboxylate, p-benzoquinone, 2-carbomethoxybenzoquinone, 2-methylbenzoquinone, 1,4-naphthoquinone, 2-methyl-1,4-naphthoquinone, and 5-hydroxy-1,4-naphthoquinone.When prepared the DTBU isomers are present in the ratio E,Z:Z,Z:E,E = 45:45:10.Of these, Z,Z-DTBU appears to be unreactive.In several cases where multible Diels-Alder products were possible, two related to E,Z- or E,E-DTBU were obtained.A connection between 1H NMR data (δ and J) and stereochemical configuration and conformation was elaborated for adducts of DTBU with p-benzoquinones or maleic anhydride.