7477-66-9 Usage
General Description
"(2E)-4-(4-bromophenyl)-4-oxobut-2-enoyl chloride" is a chemical compound with the molecular formula C10H7BrO2Cl. It is a derivative of the compound butan-2-one and is an acyl chloride, containing a chloride group attached to the acyl function. (2E)-4-(4-bromophenyl)-4-oxobut-2-enoyl chloride is often used in organic synthesis as a reagent for the preparation of various pharmaceuticals and agrochemicals. Its structure includes a butenoyl group, a bromophenyl group, and a carbonyl group, making it useful for the introduction of these functionalities into more complex molecules. As an acyl chloride, it is highly reactive and should be handled with caution in laboratory settings.
Check Digit Verification of cas no
The CAS Registry Mumber 7477-66-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,7 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 7477-66:
(6*7)+(5*4)+(4*7)+(3*7)+(2*6)+(1*6)=129
129 % 10 = 9
So 7477-66-9 is a valid CAS Registry Number.
7477-66-9Relevant articles and documents
(E)-4-Aryl-4-oxo-2-butenoic acid amides, chalcone-aroylacrylic acid chimeras: Design, antiproliferative activity and inhibition of tubulin polymerization
Vitorovic-Todorovic, Maja D.,Eric-Nikolic, Aleksandra,Kolundzija, Branka,Hamel, Ernest,Ristic, Slavica,Juranic, Ivan O.,Drakulic, Branko J.
, p. 40 - 50 (2013/05/09)
Antiproliferative activity of twenty-nine (E)-4-aryl-4-oxo-2-butenoic acid amides against three human tumor cell lines (HeLa, FemX, and K562) is reported. Compounds showed antiproliferative activity in one-digit micromolar to submicromolar concentrations.
