74794-33-5Relevant academic research and scientific papers
Synthesis of osthole derivatives with grignard reagents and their larvicidal activities on mosquitoes
Liu, Ming,Liu, Yang,Hua, Xuewen,Wu, Changchun,Zhou, Sha,Wang, Baolei,Li, Zhengming
, p. 1353 - 1358 (2016/02/18)
The structure of osthole has been modified to improve its larvicidal activity against mosquitoes. A new efficient synthesis of osthole derivatives with Grignard reagents has been developed, which employs CuI and LiCl as promoters and covers a broad range of substrates to afford the corresponding products in mild to good yields (up to 83%). Bio-activity evaluation showed that several products exhibited better activities than osthole. CuI and LiCl promoted efficient synthesis of osthole derivatives with Grignard reagents has been developed. Bio-activity evaluation showed that several products exhibited far better larvicidal activities against mosquitoes than osthole.
Synthesis of Linear Pyranocoumarins: Xanthoxyletin, 4-Methylxanthyletin, and 4-Phenylxanthyletin
Ahluwalia, Vindo Kumar,Bhat, Krishna,Prakash, Chandra,Bala, Shashi
, p. 1070 - 1072 (2007/10/02)
A convenient synthesis of linear pyranocoumarins (2H,8H-benzodipyran-2-ones), viz., xanthoxyletin, 4-methylxanthyletin and 4-phenylxanthyletin is described which uses blocking the 8-position of appropriate 7-hydroxycoumarin derivatives with iodine and 1,1-dimethyl-2-propynylation followed by cyclisation.
A Convenient Synthesis of Psoralen Derivatives: Psoralen, 4-Methyl-psoralen and 4-Phenyl-psoralen
Ahluwalia, V.K.,Prakash, Chandra,Bala, Shashi
, p. 877 - 882 (2007/10/02)
A convenient synthesis of psoralen derivatives, viz., 7H-furo benzopyran-7-one (psoralen), 5-methyl-7H-furo benzopyran-7-one (4-methyl-psoralen) and 5-phenyl-7H-furo benzopyran-7-one (4-phenyl-psoralen) by blocking the 8-position of the starting compounds with iodine, subsequent Claisen migration followed by cyclisation is described. - Keywords: Claisen migration; Coumarins; Psoralen derivatives
