74831-33-7

Upstream product

• 1613-37-2 Quinoline N-oxide 
• 106-38-7 para-bromotoluene 
• 29540-83-8 p-tolyl triflate 
• 106-43-4 para-chlorotoluene 
• 93-10-7 quinoline-2-carboxylic acid 
• 3297-64-1 2-carboxyquinoline N-oxide 
• 624-31-7 4-tolyl iodide 
• 106-49-0 p-toluidine 
• 5720-05-8 4-methylphenylboronic acid 
• 539-44-6 N-4-methylphenylhydrazine 
• 62322-75-2 1-(4-methylphenyl)-3-(2-nitrophenyl)prop-2-en-1-one 
• 18457-79-9 2-cyanoquinoline N-oxide 
• 4294-57-9 para-methylphenylmagnesium bromide 

Downstream Products

• 24667-94-5 2-(4-methylphenyl)quinoline 

Relevant academic research and scientific papers

Visible-light-promoted c2 selective arylation of quinoline and pyridine n-oxides with diaryliodonium tetrafluoroborate

A protocol of visible-light-promoted C2 selective arylation of quinoline and pyridine N-oxides, with diaryliodonium tetrafluoroborate as an arylation reagent, using eosin Y as a photocatalyst for the construction of N-heterobiaryls was presented. This met

Preparation method of 2- aryl substituted quinoline nitrogen oxide compound

The preparation method 2 - of, aryl-substituted quinoline nitrogen oxide is 2 - The method, according to the present invention provides,aryl-substituted quinoline nitrogen oxide compound, in a nitrogen atmosphere at room temperature, The method for prepar

KMnO4-mediated direct selective radical cross-coupling: An effective strategy for C2 arylation of quinoline N-oxide with arylboronic acids

Direct C[sbnd]H functionalization of quinoline N-oxides with arylboronic acids is achieved using KMnO4 as the sole and efficient oxidative system. This method provides an efficient protocol to construct regioselectively 2-arylquinoline N-oxides

Cu(OAc)2-catalyzed direct radical C2 arylation of quinoline N-oxide with arylamines

A Cu(OAc)2-catalyzed synthesis of 2-arylquinoline N-oxides with easily available arylamines is described. The main features of this reaction are mild reaction conditions, high functional-group tolerance, excellent regioselectivity, and good to excellent yields. This procedure is mild, operationally simple, and constitutes a greener approach to the arylation of quinoline N-oxides.

KMnO4-mediated direct C2-selective C?H arylation of quinoline N-oxides with aromatic hydrazines

An efficient protocol for the synthesis of 2-arylquinoline N-oxides has been developed via KMnO4-mediated cross-coupling reaction of quinoline N-oxides with aromatic hydrazines in moderated to good yields. The reactions proceeded efficiently over a broad range of substrates with excellent regioselectivity and functional group tolerance.

Carbon Nanotube-Ruthenium Hybrids for the Partial Reduction of 2-Nitrochalcones: Easy Access to Quinoline N-Oxides

A ruthenium-carbon nanotube nanohybrid was employed as a catalyst in the tandem transformation of nitrochalcones into quinoline N-oxides. Partial reduction of the nitro group to a hydroxylamine, followed by in situ intramolecular condensation to the carbo

Pd-catalyzed decarboxylative cross-coupling of 2-carboxyazine N-oxides with various (hetero)aryl halides

Decarboxylative cross-coupling reactions of substituted 2-carboxyazine N-oxides, with a variety of (hetero)aryl halides, by bimetallic Pd 0/CuI and Pd0/AgI catalysis are reported. Two possible pathways, a conven

Discovery of a full-color-tunable fluorescent core framework through direct C-H (hetero)arylation of N-heterocycles

All the colors of the rainbow! A full coverage of emission wavelengths in the visible region (405-616 nm) with large Stokes shifts in C3-Indo-Fluor may be straightforwardly and succinctly achieved by the palladium-catalyzed direct C-H arylation of indolizines at the C3 position of the pyrrole ring (see figure). The fluorophores have successfully marked A375 cells. Copyright

Chemoselective synthesis of quinoline N-oxides from 3-(2-nitrophenyl)-3- hydroxypropanones

The reaction of 3-(2-nitrophenyl)-3-hydroxypropanones with Zn/NH 4Cl gave the corresponding quinoline N-oxides in 80-90% yields. The reaction initiated the reduction of nitro group to afford the corresponding hydroxylamine, which intramolecularly condensed and followed by dehydration to give quinoline N-oxide. Although treatment of 2-nitrochalcone with Zn/NH 4Cl in EtOH/H2O resulted in the formation of quinoline N-oxide in low yield, the reaction of 2-nitrochalcone with Sn/NH4Cl in refluxing EtOH/H2O afforded quinoline N-oxide in 80% yield.