748798-77-8

Basic information

• Product Name: 2-(2-hydroxyethyl)-N-[2-(3-benzyloxyphenoxy)ethyl]benzamide
• Synonyms: 2-(2-hydroxyethyl)-N-[2-(3-benzyloxyphenoxy)ethyl]benzamide
• CAS NO: 748798-77-8
• Molecular Weight: 391.467
• Mol File: 748798-77-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-hydroxyethyl)-N-[2-(3-benzyloxyphenoxy)ethyl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-hydroxyethyl)-N-[2-(3-benzyloxyphenoxy)ethyl]benzamide(748798-77-8)
• EPA Substance Registry System: 2-(2-hydroxyethyl)-N-[2-(3-benzyloxyphenoxy)ethyl]benzamide(748798-77-8)

Safety Data

• Hazardous Substances Data: 748798-77-8(Hazardous Substances Data)

Upstream product

• 4702-34-5 isochroman-1-one 
• 85300-32-9 2-[3-(benzyloxy)phenoxy]ethylamine 
• 748798-75-6 N-{2-[3-(benzyloxy)phenoxy]ethyl}acetamide 
• 100-39-0 benzyl bromide 
• 3769-41-3 3-Benzyloxyphenol 
• 108-46-3 recorcinol 

Downstream Products

• 1026745-37-8 11-benzyloxy-5,7,8,13b-tetrahydro-6H-9-oxa-6a-aza-benzo[6,7]cyclohepta[1,2-a]naphthalene 
• 748798-78-9 2-{2-[({2-[2-(benzyloxy)phenoxy]ethyl}amino)carbonyl]phenyl}ethyl ethyl carbonate 

Relevant articles and documents

Dopamine/serotonin receptor ligands. 9.1 oxygen-containing midsized heterocyclic ring systems and nonrigidized analogues. A step toward dopamine D5 receptor selectivity

Eleven-membered heterocycles (dibenz[g,j]-1-oxa-4-azacycloundecenes) and open-chain analogues were synthesized and investigated for affinities to human dopamine receptor subtypes. The moderately rigidized rings displayed nanomolar and subnanomolar Ki values at D1-like receptors with a significant D1 to D2 and a slight D5 to D 1 selectivity. The open-chain analogues showed lower affinities but significant D1 to D2 selectivities. Compound 3 (K i(D5) = 0.57 nmol) showed antagonistic or inverse agonistic binding characteristics in a functional Ca assay.