74882-27-2

Basic information

• Product Name: 2-(2-p-benzyloxyphenylethyl)-1,3-dithian
• Synonyms: 2-(2-p-benzyloxyphenylethyl)-1,3-dithian
• CAS NO: 74882-27-2
• Molecular Weight: 330.515
• Mol File: 74882-27-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-p-benzyloxyphenylethyl)-1,3-dithian(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-p-benzyloxyphenylethyl)-1,3-dithian(74882-27-2)
• EPA Substance Registry System: 2-(2-p-benzyloxyphenylethyl)-1,3-dithian(74882-27-2)

Safety Data

• Hazardous Substances Data: 74882-27-2(Hazardous Substances Data)

Upstream product

• 836-42-0 4-benzyloxybenzyl chloride 
• 74882-12-5 2-(2-p-benzyloxyphenylethyl)-4,4,6-trimethyl-5,6-dihydro-4H-1,3-oxazine 
• 74882-14-7 2-(2-p-benzyloxyphenylethyl)-4,4,6-trimethylperhydro-1,3-oxazine 
• 50463-48-4 3-(4-benzyloxyphenyl)propanoic acid 
• 61440-45-7 3-[4-(benzyloxy)phenyl]propan-1-ol 
• 109-80-8 1.3-propanedithiol 
• 68486-77-1 3-(4-(benzyloxy)phenyl)propanal 

Downstream Products

• 19120-38-8 1,2,3-triphenylcyclopropane 
• 74882-29-4 2-(2-p-hydroxyphenylethyl)-1,3-dithian 

Relevant articles and documents

Methods for the Construction of Linear 1,7-Diarylheptanoids; Synthesis of Di-O-methylcentrolobol and Precursors (Synthetic and Biosynthetic) to the meta,meta-Bridged Biphenyls Myricanol and Myricanone

1,7-diarylheptanoids are a varied natural product class in which 'linear' types appear to be biosynthetic precursors to macro(carbo)cyclic (3), macro(oxa)cyclic (4), and condensed polycyclic (5) examples.Various methods (suitable for radiolabelling) are described for constructing 'linear' diarylheptanoids, including Grignard couplings (employing activated magnesium) with arylpropanals and oxazonium salts (11a), (11h), (15a), and (15b)> and dithian alkylation (15c)>.Alkyl-lithium treatment of the benzyloxydithian (19b) gave 1,2,3-triphenylcyclopropane.Syntheses via trialkylcyanoborates were frustrated by disproportionation of the intermediate trialkylboranes.The diarylheptanoids synthesised (11a-h) and (15a-e) include synthetic and biosynthetic precursors to meta,meta-bridged biphenyls and related macrocyclic ethers.