50463-48-4

Basic information

• Product Name: 3-[4-(BENZYLOXY)PHENYL]PROPIONIC ACID
• Synonyms: 3-[4-(benzyloxy)phenyl]propanoic acid (IM OCS);3-[4-(benzyloxy)phenyl]propanoic acid
• CAS NO: 50463-48-4
• Molecular Formula: C₁₆H₁₆O₃
• Molecular Weight: 256.3
• Mol File: 50463-48-4.mol
• Article Data: 36

Chemical Properties

• Melting Point: 116-118℃
• Boiling Point: 429.3 °C at 760 mmHg
• Flash Point: 159.4 °C
• Appearance: /
• Density: 1.175 g/cm³
• Vapor Pressure: 3.91E-08mmHg at 25°C
• Refractive Index: 1.585
• CAS DataBase Reference: 3-[4-(BENZYLOXY)PHENYL]PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-(BENZYLOXY)PHENYL]PROPIONIC ACID(50463-48-4)
• EPA Substance Registry System: 3-[4-(BENZYLOXY)PHENYL]PROPIONIC ACID(50463-48-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 50463-48-4(Hazardous Substances Data)

Usage

General Description

3-[4-(Benzyloxy)phenyl]propionic acid is a chemical compound with a molecular formula C18H16O3. Also known as Flurbiprofen, it is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the production of prostaglandins, which are responsible for inflammation and pain. It is commonly used to treat conditions such as arthritis, menstrual cramps, and minor aches and pains. The benzyloxy group is responsible for its analgesic and anti-inflammatory properties. It is available in various forms, including oral tablets and topical creams, and is generally considered safe when used as directed by a healthcare professional. However, like all NSAIDs, it may have potential side effects, such as stomach bleeding, kidney problems, and an increased risk of heart attack or stroke, especially with long-term use.

InChI:InChI=1/C16H16O3/c17-16(18)11-8-13-6-9-15(10-7-13)19-12-14-4-2-1-3-5-14/h1-7,9-10H,8,11-12H2,(H,17,18)

Upstream product

• 501-97-3 4-hydroxyphenylpropionic acid 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 5597-50-2 3-(4-hydroxyphenyl)propionic acid methyl ester 
• 100-51-6 benzyl alcohol 
• 58608-97-2 3-(4-benzyloxyphenyl)propionic acid benzyl ester 
• 7400-08-0 para-coumaric acid 
• 836-42-0 4-benzyloxybenzyl chloride 
• 84184-50-9 diethyl 2-(4-benzyloxybenzyl)malonate 
• 836-43-1 4-benzyloxybenzyl alcohol 
• 7400-08-0 p-Coumaric Acid 
• 24807-40-7 methyl 3-(4-benzyloxyphenyl)propanoate 

Downstream Products

• 24807-40-7 methyl 3-(4-benzyloxyphenyl)propanoate 
• 134446-80-3 4-Decyl-benzoic acid 4-(2-heptyloxycarbonyl-ethyl)-phenyl ester 
• 134446-83-6 4-Decyloxy-benzoic acid 4-(2-heptyloxycarbonyl-ethyl)-phenyl ester 
• 134446-94-9 Cyclohexane-1,4-dicarboxylic acid bis-[4-(2-heptyloxycarbonyl-ethyl)-phenyl] ester 
• 139446-84-7 4-Hydroxy-3'-oxodecylbenzene 
• 58608-95-0 3-(4-hydroxyphenyl)-N-phenylpropanamide 
• 58609-02-2 N-(4-chlorophenyl)-3-(4-hydroxyphenyl)propanamide 
• 58609-37-3 2-Methyl-2-[4-(2-phenylcarbamoyl-ethyl)-phenoxy]-propionic acid 
• 58609-34-0 {4-[2-(4-Chloro-phenylcarbamoyl)-ethyl]-phenoxy}-acetic acid 
• 58608-99-4 3-(4-Benzyloxy-phenyl)-N-phenyl-propionamide 
• 58609-36-2 {4-[2-(2-Methoxy-phenylcarbamoyl)-ethyl]-phenoxy}-acetic acid 
• 58608-96-1 2-Methyl-2-[4-(2-phenylcarbamoyl-ethyl)-phenoxy]-propionic acid ethyl ester 
• 58609-01-1 3-(4-Benzyloxy-phenyl)-N-(4-chloro-phenyl)-propionamide 
• 58609-38-4 2-{4-[2-(4-Chloro-phenylcarbamoyl)-ethyl]-phenoxy}-2-methyl-propionic acid 

Relevant articles and documents

Computer-Aided Fragment Growing Strategies to Design Dual Inhibitors of Soluble Epoxide Hydrolase and LTA4 Hydrolase

Multitarget ligands are interesting candidates for drug discovery and development due to improved safety and efficacy. However, rational design and optimization of multitarget ligands is tedious because affinity optimization for two or more targets has to be performed simultaneously. In this study, we demonstrate that, given a molecular fragment, which binds to two targets of interest, computer-aided fragment growing can be applied to optimize compound potency, relying on either ligand- or structure-derived information. This methodology is applied to the design of dual inhibitors of soluble epoxide hydrolase and leukotriene A4 hydrolase.

Benzoic hydroxamate-based iron complexes as model compounds for humic substances: Synthesis, characterization and algal growth experiments

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POLYMERIZABLE CHIRAL COMPOUND

The present invention refers to, a strong HTP and a, a lower melting point as chiral compounds having a diffusion barrier it is an object to provide an 1/10 time as large as that of. Said liquid crystal aberration correcting element, general formula (I) Polymerizable chiral reagent represented by compound. Subject to the compounds of the invention herein having a melting and low HTP, since a color compound melting portion of the electron emitting material paste excellent drives liquid crystal composition, is useful as a components. Furthermore, as a component compound polymerizable chiral reagent of the invention herein a polymerizable liquid crystal composition, to produce large-sized content of compound polymerizable chiral reagent of the insertion part and the holder and having excellent optical characteristics and operating method of anisotropic body group represented by the formula 1.. A optically anisotropic product, of the invention herein, the deflecting plates, retardation plate and the like useful.