7496-50-6

Usage

Uses

Used in Pharmaceutical Industry:
6-METHYL-4,5,6,7-TETRAHYDRO-1,3-BENZOTHIAZOL-2-AMINE HYDROCHLORIDE is used as a precursor in the synthesis of various drugs for its unique molecular structure and diverse biological activities.
Used in Medicinal Chemistry Research:
6-METHYL-4,5,6,7-TETRAHYDRO-1,3-BENZOTHIAZOL-2-AMINE HYDROCHLORIDE is used as a research compound for exploring its potential applications in medicinal chemistry due to its diverse biological properties.
Used in Drug Discovery:
6-METHYL-4,5,6,7-TETRAHYDRO-1,3-BENZOTHIAZOL-2-AMINE HYDROCHLORIDE is used as a candidate in drug discovery for its potential to contribute to the development of new therapeutic agents, particularly in the areas of antiviral, antibacterial, and antifungal treatments.
Used in Pharmaceutical Formulations:
6-METHYL-4,5,6,7-TETRAHYDRO-1,3-BENZOTHIAZOL-2-AMINE HYDROCHLORIDE is used as an ingredient in pharmaceutical formulations to enhance solubility and bioavailability, improving the compound's effectiveness in treating various conditions.

InChI:InChI=1/C8H12N2S/c1-5-2-3-6-7(4-5)11-8(9)10-6/h5H,2-4H2,1H3,(H2,9,10)/t5-/m1/s1

Upstream product

• 39512-00-0 4-methyl-2-chlorocyclohexanone 
• 5392-23-4 2-mercapto-4,4,6-trimethyl-1,4-dihydro-pyrimidine 
• 589-92-4 1-methylcyclohexan-4-one 
• 17356-08-0 thiourea 
• 27579-55-1 2-bromo-4-methylcyclohexanone 
• 89886-68-0 2-bromo-5-methylcyclohexanone 
• 591-24-2 3-Methylcyclohexanone 
• 38671-78-2 4-methyl-1-(trimethylsilyloxy)-1-cyclohexene 

Downstream Products

• 63208-70-8 7-methyl-2-(4-nitro-phenyl)-5,6,7,8-tetrahydro-benzo[d]imidazo[2,1-b]thiazole 
• 63208-72-0 2-biphenyl-4-yl-7-methyl-5,6,7,8-tetrahydro-benzo[d]imidazo[2,1-b]thiazole 
• 63208-68-4 7-methyl-2-phenyl-5,6,7,8-tetrahydro-benzo[d]imidazo[2,1-b]thiazole 
• 63208-71-9 7-methyl-2-p-tolyl-5,6,7,8-tetrahydro-benzo[d]imidazo[2,1-b]thiazole 
• 63208-69-5 2-(4-chlorophenyl)-7-methyl-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b][1,3]thiazole 
• 63208-78-6 2-amino-6-methyl-3-(2-oxo-2-p-tolyl-ethyl)-4,5,6,7-tetrahydro-benzothiazolium; bromide 
• 1419221-46-7 N-(6-methyl-4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide 

Relevant academic research and scientific papers

HMOX1 inducers

The present invention is related to compounds of structure (I) as heme oxygenase 1 (HMOX 1) inducers. The present invention is also related a method of controlling the activity or the amount, or both the activity and the amount, of heme-oxygenase 1 in a mammalian subject. The definitions of the variables are provided herein.

Discovery of imidazo[2,1- b ]thiazole HCV NS4B inhibitors exhibiting synergistic effect with other direct-acting antiviral agents

The design, synthesis, and SAR studies of novel inhibitors of HCV NS4B based on the imidazo[2,1-b]thiazole scaffold were described. Optimization of potency with respect to genotype 1b resulted in the discovery of two potent leads 26f (EC50 = 16

Facile Synthesis of Aminothiazoles

The reaction of thioureas with ketones in the presence of N-bromosuccinimide furnishes 2-aminothiazoles.The method is quick, convenient and versatile.

Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides

This invention encompasses orally effective antiulcer agents of the formula STR1 wherein X is hydroxy, (C1 -C5)-alkoxy, phenoxy, benzyloxy, or --NH(CH2)n Y wherein n is an integer of value 2 to 4 and Y is di-(C1 -C3)-alkylamino, 1-pyrrolidinyl, 1-piperidinyl or 4-morpholinyl; R' and R" when taken together are (C3 -C8)-alkylene, with the proviso that the ring so formed is 5- to 8-membered; R' and R" when taken separately are each independently hydrogen, (C1 -C6)-alkyl or (C5 -C6)-cycloalkyl, with the proviso that when X is other than --NH(CH2)n Y, at least one of R' and R" is other than hydrogen; the pharmaceutically acceptable cationic salts thereof when X is hydroxyl, and the pharmaceutically acceptable anionic salts thereof when X is --NH(CH2)n Y.