74973-28-7Relevant academic research and scientific papers
Conjugate addition of RMgX-3MeLi to α,β-unsaturated amides and α,β-unsaturated carboxylic acids
Kikuchi, Mikiko,Niikura, Satomi,Chiba, Nao,Terauchi, Nahoko,Asaoka, Mono
, p. 736 - 737 (2007)
In the presence of 3 equivalents of MeLi, various Grignard reagents reacted with secondary α,β-unsaturated amides and α,β-unsaturated carboxylic acids to give the corresponding Michael adducts in good yields. Copyright
Bromo Radical-Mediated Photoredox Aldehyde Decarbonylation towards Transition-Metal-Free Hydroalkylation of Acrylamides at Room Temperature
Sun, Zhaozhao,Huang, Huawen,Wang, Qiaolin,Deng, Guo-Jun
supporting information, p. 453 - 458 (2021/12/03)
Herein, we report a visible-light-mediated hydroalkylation reaction of alkenes using easily available aldehydes as alkyl sources via bromo radical-promoted photoredox decarbonylation. This protocol provides an alternative entry to C(sp3)?C(sp3) bond formation and features considerable advantages including mild and clean reaction conditions, obviation for transition-metal catalyst, and good functional group compatibility.
CONJUGATE ADDITION OF ORGANOLITHIUM REAGENTS TO ACRYLANILIDE ANIONS
Baldwin, Jack E.,Dupont, William A.
, p. 1881 - 1882 (2007/10/02)
Phenyllithium, n-butyllithium, and t-butyllithium were found to add to substituted acrylanilide anions to give the 1,4-addition products in fair to good yields.
