7498-40-0

Usage

Uses

Used in Pharmaceutical Industry:
(4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE is used as an intermediate for the synthesis of various pharmaceuticals due to its unique chemical structure and reactivity. Its ability to be incorporated into more complex molecules makes it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical industry, (4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE is used as an intermediate in the production of various agrochemicals, contributing to the development of new pesticides and other agricultural products.
Used in Cancer Treatment Research:
(4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE is used as a potential therapeutic agent in cancer treatment research. Its investigation into the treatment of various diseases, including cancer, highlights its potential as a compound with significant medical applications.
Used in Antimicrobial Applications:
(4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE is used as an antimicrobial agent due to its demonstrated antimicrobial properties. It can be utilized in the development of new antimicrobial products, contributing to the fight against resistant bacteria and other pathogens.
Used in Material Science:
(4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE is used as a building block in the development of novel materials. Its unique chemical structure allows it to be incorporated into new materials with specific properties, such as improved strength or chemical resistance.
Used in Chemical Reactions as a Reagent:
As a reagent in chemical reactions, (4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE is used to facilitate specific transformations and syntheses of other complex organic molecules, further expanding its utility in the field of chemistry.

InChI:InChI=1/C12H9N3O3/c16-12(14-11-3-1-2-8-13-11)9-4-6-10(7-5-9)15(17)18/h1-8H,(H,13,14,16)

Upstream product

• 504-29-0 2-aminopyridine 
• 122-04-3 4-nitro-benzoyl chloride 
• 5918-77-4 2-<(p-nitrobenzylidene)amino>pyridine 
• 86843-82-5 p-nitrobenzoyl chloride 
• 100-12-9 4-ethylnitrobenzene 
• 100-19-6 (4-nitrophenyl)ethanone 
• 109-09-1 2-chloropyridine 
• 619-80-7 4-nitrobenzamide 
• 62-23-7 4-nitro-benzoic acid 
• 555-16-8 4-nitrobenzaldehdye 
• 14150-95-9 2-aminopyridine N-oxide 

Downstream Products

• 7467-42-7 4-amino-N-(pyridin-2-yl)benzamide 
• 86843-97-2 2-(4-Nitro-phenyl)-[1,2,4]triazolo[1,5-a]pyridine 
• 86843-89-2 2-[5-(4-Nitro-phenyl)-tetrazol-1-yl]-pyridine 
• 686290-12-0 (1-naphthyl)[N-(2-pyridyl)-4-nitrobenzamido](triphenylphosphine)nickel(II) 
• 1261035-37-3 N-(pyridin-2-yl)-4-stearamidobenzamide 
• 1261035-36-2 N-(pyridine-2-yl)-4-dodecanamido-benzamide 
• 1372892-86-8 4-((3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)-N-(pyridin-2-yl)benzamide 
• 96830-01-2 N-Methyl-4-nitro-N-pyridin-2-yl-benzamide 

Relevant academic research and scientific papers

ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION

The present invention relates to a compound of formula (I) wherein X1 represents an alkenylene group, a -NH-CO- group, a -CO-NH- group, Y1 represents an aryl group selected from a pyridyl group, a pyrazinyl group or a pyrimidinyl group, X2 represents a -O- group, a-CO-NH- group, a -NH-CO-NH- group, a -OCH2- group, a -NH-CO- group, a divalent 5-membered heteroaromatic ring comprising 1, 2, 3 or 4 heteroatoms or a -SO2-NH- group, and Y2 represents a hydrogen atom, a hydroxyl group, a morpholinyl group, a piperidinyl group, optionally substituted by a (C1-C4)alkyl group, a piperazinyl group, optionally substituted by a (C1-C4)alkyl group, or a -CR1R2R3 group or alternatively X2-Y2 represents a group -CONRcRd, wherein Rc and Rd form, together with the nitrogen atom a heterocyclic ring, optionally substituted by one or two (C1-C4)alkyl group, by a cyclopentyl group thus forming a spirocyclopentyl, or by a trifluoromethyl group, or any of its pharmaceutically acceptable salt, for use in the treatment and/or prevention of a RNA virus infection caused by a RNA virus belonging to group IV or V of the Baltimore classification. The present invention further relates to new compounds, to pharmaceutical compositions containing them and to synthesis process for manufacturing them.

Direct Transformation of Alkylarenes into N-(Pyridine-2-yl)amides by C(sp3)–C(sp3) Bond Cleavage

C(sp3)–H bond functionalization and C(sp3)–C(sp3) bond cleavage are very challenging transformations in chemistry. Herein, we report a mild and green methodology for the construction of N-(pyridine-2-yl)amides via tandem C(sp3)–H activation/C–C bond cleavage of alkylarenes. Various N-heterocyclic amides were directly synthesized from alkylarenes in water in moderate to good yields.

CuI incorporated cobalt ferrite nanoparticles as a magnetically separable catalyst for oxidative amidation reaction

A Cu-incorporated magnetic nanocatalyst (CoFe2O4?SiO2-SH-CuI) has been developed by immobilizing CuI on the modified surface of CoFe2O4 magnetic nanoparticles. The surface of the silica coated cobalt

1,1-Difluoro-3-aryl(heteroaryl)-1: H -pyrido[1,2- c] [1,3,5,2]oxadiazaborinin-9-ium-1-uides: Synthesis; Structure; and photophysical, electrochemical, and BSA-binding studies

This paper presents a series of six examples of 1,1-difluoro-3-aryl(heteroaryl)-1H-pyrido[1,2-c][1,3,5,2]oxadiazaborinin-9-ium-1-uides (2) - in which aryl(heteroaryl) = phenyl, 4-MeC6H4, 4-N(CH3)2C6H

Metal-Free Synthesis of N-(Pyridine-2-yl)amides from Ketones via Selective Oxidative Cleavage of C(O)-C(Alkyl) Bond in Water

The TBHP/TBAI-mediated synthesis of N-(pyridine-2-yl)amides in water from ketones and 2-aminopyridine via direct oxidative C-C bond cleavage has been developed. A series of ketones, including more challenging inactive aromatic ketones substituted with div

AMINONAPTHOQUINONE COMPOUNDS AND PHARMACEUTICAL COMPOSITION FOR BLOCKING UBIQUITINATION-PROTEASOME SYSTEM IN DISEASES

The invention relates to new compounds with low cytotoxicity for blocking the ubiquitination- proteasome system in diseases. Accordingly, these compounds can be used in treatment of disorders including, but not limited to, cancers, neurodegenerative diseases, inflammatory disorders, autoimmune disorders and metabolic disorders.

Microwave-assisted heteropolyanion-based ionic liquid promoted sustainable protocol to N-heteroaryl amides via N-directing dual catalyzed oxidative amidation of aldehydes

A sustainable procedure for the synthesis of N-heteroaryl amides directly from oxidative amidation of aldehydes catalyzed by heteropolyanion-based ionic liquids under microwave-promoted conditions has been reported. The transformation has proven to tolerate a wide range of aldehydes and amino heterocycles with different functional groups. Moderate to excellent yields, solvent-free media, operational simplicity and reusability of catalysts are the main highlights. Furthermore, the proposed N-directing dual-catalysis mechanistic pathway was briefly investigated in this report.

Metal-free oxidative amidation of aldehydes with aminopyridines employing aqueous hydrogen peroxide

The first metal free report on the amidation of aldehydes with aminopyridines was accomplished using simple aqueous hydrogen peroxide (aq. H2O2) as the oxidant. No catalysts or additives were needed for this transformation and the reaction proceeded in water, an environmentally benign reaction medium. Green oxidant and reaction conditions, and the ability to construct diverse N-(pyridin-2-yl)benzamide by this elegant method render it a practical alternative for the synthesis of these amides.

ORGANIC MOLECULES FOR TERAHERTZ TAGGING APPLICATIONS

The present invention discloses substituted heterocyclic compounds and /or aromatic compounds containing amide and/or urea groups exhibiting resonance in the range of 0.1- 10 THz. The invention also discloses binary molecular complexes based on the substituted heterocyclic compounds and/or aromatic compounds containing amide and/or urea groups of the present invention. The compounds and binary molecular complexes of the present invention have varying molecular mass and hydrogen bond strengths demonstrating several resonances below 10 THz. The compounds and binary molecular complexes of the present invention are customizable for various applications, such as authentication of a product.

A one-pot copper catalyzed biomimetic route to n -heterocyclic amides from methyl ketones via oxidative c-c bond cleavage

A direct one-pot Cu-catalyzed biomimetic oxidation of methyl ketones to pharmaceutically important N-heterocyclic amides is reported. The scope of the method is broad, scalable, and mild, and the reaction is tolerant with various acid, base sensitive functionalities with multiple heteroatoms and aryl halides. The extensive mechanistic studies suggest that this reaction follows the Luciferin-Luciferase-like pathway.