749861-31-2 Usage
Type of compound
Spiro compound
Elements present
Carbon (C), Hydrogen (H), Nitrogen (N), and Oxygen (O)
Structure
Contains a nitrogen and oxygen at the spiro junction
Functional groups
Ketone (C=O), two methoxy groups (-OCH3)
Substitution pattern
8,8-diMethoxy-
Pharmaceutical applications
Used in various pharmaceutical and medicinal applications
Synthesis utility
Valuable building block for the synthesis of other organic compounds
Biological and pharmacological activities
Potential activities, but further research is needed
Solubility
Not mentioned in the material provided
Stability
Not mentioned in the material provided
Reactivity
Not mentioned in the material provided
Physical state
Not mentioned in the material provided
Melting or boiling point
Not mentioned in the material provided
Density
Not mentioned in the material provided
Optical properties
Not mentioned in the material provided
Hazards and safety
Not mentioned in the material provided
Check Digit Verification of cas no
The CAS Registry Mumber 749861-31-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,9,8,6 and 1 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 749861-31:
(8*7)+(7*4)+(6*9)+(5*8)+(4*6)+(3*1)+(2*3)+(1*1)=212
212 % 10 = 2
So 749861-31-2 is a valid CAS Registry Number.
749861-31-2Relevant articles and documents
CYCLIC CYANOENONE DERIVATIVES AS MODULATORS OF KEAP1
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Page/Page column 123, (2022/01/24)
The present invention relates to cyclic cyanoenone derivatives of Formula (I) or pharmaceutically acceptable salts or solvates thereof, wherein R1, R2, R3, R4 and m are as defined herein. The present invention also relates to pharmaceutical compositions comprising the cyclic cyanoenone derivatives of Formula (I) and to their use in therapy.
Stereocontrolled total synthesis of potent immunosuppressant FR901483
Kan, Toshiyuki,Fujimoto, Teppei,Ieda, Shigeru,Asoh, Yusuke,Kitaoka, Haruka,Fukuyama, Tohru
, p. 2729 - 2731 (2007/10/03)
A total synthesis of the potent immunosuppressant FR901483 (1) has been accomplished. The key feature of our convergent synthesis is the stereoselective incorporation of the p-methoxybenzyl and methylamino groups within the core moiety 10. Tricycle 10 was
