83935-54-0

Usage

Uses

Used in Pharmaceutical Industry:
DI-METHYL-4-NITRO-4-[2-(METHOXYCARBONYL)ETHYL]HEPTANEDIOATE serves as a chemical intermediate in the pharmaceutical industry, playing a crucial role in the synthesis of various organic molecules and drugs. Its unique structure allows for the development of new therapeutic agents with potential applications in treating a range of medical conditions.
Used in Agrochemical Industry:
In the agrochemical industry, DI-METHYL-4-NITRO-4-[2-(METHOXYCARBONYL)ETHYL]HEPTANEDIOATE is utilized for the production of pesticides, herbicides, and insecticides. Its chemical properties make it a valuable component in the development of effective and targeted agricultural chemicals that can protect crops and enhance agricultural productivity.
Used in Research and Development:
DI-METHYL-4-NITRO-4-[2-(METHOXYCARBONYL)ETHYL]HEPTANEDIOATE is also employed in research and development laboratories. Its unique chemical properties make it an interesting subject for scientific exploration, potentially leading to the discovery of new applications and advancements in various fields, including materials science, chemical engineering, and biotechnology.

Upstream product

• 75-52-5 nitromethane 
• 292638-85-8 acrylic acid methyl ester 
• 67-56-1 methanol 

Downstream Products

• 59085-15-3 4-(2-carboxyethyl)-4-nitroheptanedioic acid 
• 749861-03-8 1-aza-spiro[4.5]decane-2,8-dione 
• 749861-31-2 8,8-dimethoxy-1-aza-spiro[4.5]decan-2-one 
• 749861-28-7 8-hydroxy-2-oxo-1-azaspiro[4.5]dec-7-ene-7-carboxylic acid methyl ester 
• 749861-39-0 6,8-dihydroxyoctahydro-3H-7,10a-methanopyrrolo[1,2-a]azocin-3-one 
• 686723-63-7 1,4-dioxa-9-azadispiro[4.2.48.25]tetradecan-10-one 
• 193603-20-2 4-Nitro-4-(2-trityloxycarbamoyl-ethyl)-heptanedioic acid bis-(trityloxy-amide) 
• 193603-23-5 4-[2-(Benzyloxy-octyl-carbamoyl)-ethyl]-4-nitro-heptanedioic acid bis-(benzyloxy-octyl-amide) 
• 193603-22-4 4-[2-(Benzyloxy-butyl-carbamoyl)-ethyl]-4-nitro-heptanedioic acid bis-(benzyloxy-butyl-amide) 
• 141621-27-4 4-(2-Benzyloxycarbamoyl-ethyl)-4-nitro-heptanedioic acid bis-(benzyloxy-amide) 

Relevant academic research and scientific papers

ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF

Described herein are compounds of Formula (S-I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.

A simple and highly efficient procedure for construction of quaternary carbons centers by tributylphosphine catalyzed bis-Michael addition

The tributylphosphine-catalyzed bis-Michael addition reaction of various kinds of α,β-unsaturated carbonyl compounds with active methylenes is described. This is a convenient and rapid method for generating quaternary carbons centers and useful procedure for the synthesis of branched core and highly substituted trans cyclohexanones. All the reactions were completed in 60 min and afford the corresponding products in excellent yields.

Stereocontrolled total synthesis of (±)-FR901483

The total synthesis of potent immunosuppressant FR901483 (1) is reported. The remarkable feature of our convergent synthesis is the p-methoxybenzyl and methylamino groups are stereoselectively incorporated within the tri-cyclic core skeleton. The skeleton

Stereocontrolled total synthesis of potent immunosuppressant FR901483

A total synthesis of the potent immunosuppressant FR901483 (1) has been accomplished. The key feature of our convergent synthesis is the stereoselective incorporation of the p-methoxybenzyl and methylamino groups within the core moiety 10. Tricycle 10 was

Phase-transfer-catalysed Preparation of N-Alkylated Trihydroxamic Acids

We describe a synthetic route involving phase transfer catalysis leading to a series of tripodal N-alkylated hydroxamic acids as models of desferrioxamine; iron(III) exchange reactions between their iron complexes and EDTA were investigated.

Reaction of Novel Imide Reducing Reagents with Pyrrolizidinediones

The reduction of pyrrolizidinediones 4a and 4b with (i-Bu)2AlH and LiBHEt3 affords the corresponding hexahydro-5-hydroxy-3H-pyrrolizin-3-ones 8a and 8b in good yield.LiBHEt3 also reduces N-methylglutarimide (18) in 53percent yield.The combination of NaBH4/MeOH/Ac2O/CH2Cl2 selectivity reduces an imide in the presence of an ester.Hexahydro-5-(methylthio)-3H-pyrrolizin-3-ones are products of the NaBH4 reduction of pyrrolizidinediones in MeSH/CH2Cl2/Ac2O.The reduction products, thioethers (5a-c) and lactamols (8a-c), are intermediates in the synthesis of pyrrolizinones 1a-c.