749861-03-8 Usage
Uses
Used in Pharmaceutical Industry:
1-Azaspiro[4.5]decane-2,8-dione is used as a key intermediate for the synthesis of various pharmaceuticals due to its unique structure and potential biological activities. It contributes to the development of new drugs with therapeutic applications.
Used in Agrochemical Industry:
1-Azaspiro[4.5]decane-2,8-dione is utilized as a building block in the synthesis of agrochemicals, such as pesticides and herbicides, due to its potential to enhance the effectiveness and selectivity of these compounds.
Used in Medicinal Chemistry Research:
1-Azaspiro[4.5]decane-2,8-dione is employed as a valuable target for synthetic chemists and researchers in the field of medicinal chemistry. Its unique structure and potential biological activities make it an important compound for exploring new drug candidates and chemical compounds with therapeutic potential.
Used in Drug Discovery:
1-Azaspiro[4.5]decane-2,8-dione plays a crucial role in drug discovery, as its diverse range of applications and potential biological activities make it an attractive target for the development of new therapeutic agents and chemical compounds with potential applications in various medical fields.
Check Digit Verification of cas no
The CAS Registry Mumber 749861-03-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,9,8,6 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 749861-03:
(8*7)+(7*4)+(6*9)+(5*8)+(4*6)+(3*1)+(2*0)+(1*3)=208
208 % 10 = 8
So 749861-03-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H13NO2/c11-7-1-4-9(5-2-7)6-3-8(12)10-9/h1-6H2,(H,10,12)
749861-03-8Relevant articles and documents
Stereocontrolled total synthesis of potent immunosuppressant FR901483
Kan, Toshiyuki,Fujimoto, Teppei,Ieda, Shigeru,Asoh, Yusuke,Kitaoka, Haruka,Fukuyama, Tohru
, p. 2729 - 2731 (2004)
A total synthesis of the potent immunosuppressant FR901483 (1) has been accomplished. The key feature of our convergent synthesis is the stereoselective incorporation of the p-methoxybenzyl and methylamino groups within the core moiety 10. Tricycle 10 was
Stereocontrolled total synthesis of (±)-FR901483
Ieda, Shigeru,Asoh, Yusuke,Fujimoto, Teppei,Kitaoka, Haruka,Kan, Toshiyuki,Fukuyama, Tohru
, p. 721 - 738 (2009)
The total synthesis of potent immunosuppressant FR901483 (1) is reported. The remarkable feature of our convergent synthesis is the p-methoxybenzyl and methylamino groups are stereoselectively incorporated within the tri-cyclic core skeleton. The skeleton
ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF
-
, (2016/04/20)
Described herein are compounds of Formula (S-I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.
