7511-43-5

Basic information

• Product Name: 2-methyl-2,3-diphenyl-propanoic acid
• Synonyms: 2-methyl-2,3-diphenyl-propanoic acid
• CAS NO: 7511-43-5
• Molecular Formula: C₁₆H₁₆O₂
• Molecular Weight: 240.297
• Mol File: 7511-43-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 354.2°Cat760mmHg
• Flash Point: 251.1°C
• Appearance: /
• Density: 1.136g/cm³
• Vapor Pressure: 1.26E-05mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: 2-methyl-2,3-diphenyl-propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-2,3-diphenyl-propanoic acid(7511-43-5)
• EPA Substance Registry System: 2-methyl-2,3-diphenyl-propanoic acid(7511-43-5)

Safety Data

• Hazardous Substances Data: 7511-43-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H16O2/c1-16(15(17)18,14-10-6-3-7-11-14)12-13-8-4-2-5-9-13/h2-11H,12H2,1H3,(H,17,18)

Upstream product

• 101111-23-3 2-Brommethyl-2,3-diphenyl-propionsaeure 
• 124-38-9 carbon dioxide 
• 833-81-8 1,2-diphenylpropene 
• 74-83-9 methyl bromide 
• 94942-89-9 2,3-diphenylpropanoic acid 
• 35030-49-0 Methyl 2,3-diphenylpropanoate 
• 101094-41-1 2-(4-bromophenyl)-2-phenylpropane 
• 40743-08-6 1-methoxy-1,1-diphenylethane 
• 778-22-3 2,2-diphenylpropane 
• 1823-91-2 1-phenylethyl cyanide 
• 100-44-7 benzyl chloride 
• 83026-52-2 2-hydroxy-2,3-diphenylpropionic acid methyl ester 
• 41366-89-6 methyl 2-acetoxy-2,3-diphenylpropionate 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 

Downstream Products

• 1216634-44-4 C₂₁H₂₆N₂O 
• 118753-79-0 N-methyl-1,2-diphenyl-2-propylamine 
• 78141-32-9 2-methyl-1,2-diphenylpentan-3-one 
• 1985-96-2 1,2-diphenyl-2-methylpropane 
• 127867-80-5 2-benzyl-2-phenylpropanoyl chloride 
• 5814-85-7 1,2-diphenylpropane 
• 120506-00-5 3-Methyl-3-phenylsulfanyl-nonan-2-one 
• 81290-09-7 2-trimethylsilyl-1,2-diphenylpropane 
• 60905-32-0 1,2-Diphenyl-2-propylmethyl sulfid 

Relevant articles and documents

Harnessing Applied Potential: Selective β-Hydrocarboxylation of Substituted Olefins

The construction of carboxylic acid compounds in a selective fashion from low value materials such as alkenes remains a long-standing challenge to synthetic chemists. In particular, β-addition to styrenes is underdeveloped. Herein we report a new electrosynthetic approach to the selective hydrocarboxylation of alkenes that overcomes the limitations of current transition metal and photochemical approaches. The reported method allows unprecedented direct access to carboxylic acids derived from β,β-trisubstituted alkenes, in a highly regioselective manner.

Nickel-Catalyzed oxidative coupling of unactivated C(sp3)-H bonds in aliphatic amides with terminal alkynes

In this work, we demonstrated Ni-catalyzed oxidative coupling of unactivated C(sp3)-H bonds with terminal alkynes for construction of C(sp3)-C(sp) bonds to synthesize alkyl-substituted internal alkynes. Different amides exhibited good compatibility. Preliminary mechanistic studies were conducted to account for this alkynylation.

Rearrangement of Ketones. Part 4. Aluminium Chloride Catalysed Rearrangement of Some 2,2-Dialkyl-1-phenyl-1-propan-1-ones

Four α,α,α-trisubstituted acetophenones ((1):R1=R2=R3=CH3; (2):R1=R2=CH3, R3=CH2CH3; (3):R1=R2=CH3, R3=CH2Ph; (4):R1=CH3, R2=CH2CH3, R3=CH2Ph) were prepared.Ketones (1)-(4) were treated with aluminium chloride to induce rearrangement to alkyl ketones.The phenyl ketones behaved as follows: (1) gave 3-methyl-3-phenylbutan-2-one (7), (2) gave 3-methyl-3-phenylpentan-2-one (8) and 2-methyl-2-phenylpentan-3-one (9), (3) gave 3-methyl-3,4-diphenylbutan-2-one (10) and 3-methyl-1,3-diphenylbutan-2-one (11), and (4) gave 3-methyl-1,3-diphenylpentan-2-one (12), 2-methyl-1,2-diphenylpentan-3-one (13) and 3-benzyl-3-phenylpentan-2-one (14).A tentative mechanism for the rearrangement is proposed.