75115-26-3

Upstream product

• 75115-28-5 N⁽³⁾-benzylpyridine-3,4-diamine 
• 122-51-0 orthoformic acid triethyl ester 
• 100-46-9 benzylamine 
• 13534-98-0 3-bromopyridin-4-amine 
• 1346534-45-9 C₁₂H₁₁ClN₂ 
• 77287-34-4 formamide 
• 1565870-88-3 C₁₇H₁₉ClN₂O₂ 
• 1068976-14-6 tert-butyl (4-chloropyridin-3-yl)carbamate 
• 2770-01-6 4-chloro-1H-imidazo[4,5-c]pyridine 
• 100-39-0 benzyl bromide 
• 120537-44-2 3-benzyl-4-chloro-3H-imidazo<4,5-c>pyridine 
• 105942-38-9 5-benzylimidazo<4,5-c>pyridine 

Downstream Products

• 120759-74-2 3-benzylimidazo<4,5-c>pyridine-2-thione 

Relevant academic research and scientific papers

Rapid construction of imidazopyridines from ortho-haloaminopyridines

A practical strategy for the preparation of imidazopyridine derivatives from ortho-haloaminopyridines utilizing a two-step C-N coupling/cyclization reaction sequence has been developed. This procedure provides rapid and efficient access to many medicinally interesting imidazopyridine compounds and related imidazopyrazine/purine heterocycles.

Copper- and palladium-catalyzed amidation reactions for the synthesis of substituted imidazo[4,5-c]pyridines

Imidazo[4,5-c]pyridines were synthesized in three steps utilizing a palladium-catalyzed amidation/cyclization strategy. N-Aryl substrates were synthesized using copper-catalyzed amidation of 3-amino-N-Boc-4-chloropyridine. Complementary protocols for the selective chlorination of imidazo[4,5-c] pyridines at the C2 and C7 positions were also developed.

Synthesis and anticonvulsant activity of 1-benzyl-4-alkylamino-1H-imidazo[4,5-c]pyridines

Four 3-deaza analogues of the potent anticonvulsant purine, BW A78U, were synthesized and tested for anticonvulsant activity. The imidazo[4,5-c]pyridines 9-12 were prepared in two steps from 4-chloro-1H-imidazo[4,5-c]pyridine (2).The compounds were potent